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AlkB Enzymes
Known as:
Alkylation Repair Homologs
, Enzymes, AlkB
, Alkylated DNA Repair Protein AlkB Homologs
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A family of alpha- KETOGLUTARIC ACID and Fe(II)-dependent dioxygenases that are homologous to AlkB, an enzyme that repairs alkylated nucleic acids in…
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National Institutes of Health
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Related topics
Related topics
7 relations
In Blood
Process of secretion
antagonists & inhibitors
aspects of radiation effects
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Multi-substrate selectivity based on key loops and non-homologous domains: new insight into ALKBH family
Baofang Xu
,
Dongyang Liu
,
Zerong Wang
,
Ruixia Tian
,
Yongchun Zuo
Cellular and Molecular Life Sciences
2020
Corpus ID: 220417138
AlkB homologs (ALKBH) are a family of specific demethylases that depend on Fe 2+ and α-ketoglutarate to catalyze demethylation on…
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2020
2020
Identification of a Conserved Prophenoloxidase Activation Pathway in Cotton Bollworm Helicoverpa armigera
Qianran Wang
,
Mengyi Yin
,
+4 authors
Manli Wang
Frontiers in Immunology
2020
Corpus ID: 218489184
Melanization is a prominent insect humoral response for encapsulation of and killing invading pathogens. It is mediated by a…
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2020
2020
Biocatalytic Alkylation Cascades: Recent Advances and Future Opportunities for Late‐Stage Functionalization
I. McKean
,
P. Hoskisson
,
G. Burley
ChemBioChem
2020
Corpus ID: 218908486
This Concept article describes the latest developments in the emerging area of late‐stage biocatalytic alkylation. Central to…
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2017
2017
CpG promoter methylation of the ALKBH3 alkylation repair gene in breast cancer
Olafur A. Stefansson
,
Stefan Hermanowicz
,
+6 authors
S. Sigurdsson
BMC Cancer
2017
Corpus ID: 255841878
DNA repair of alkylation damage is defective in various cancers. This occurs through somatically acquired inactivation of the…
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2015
2015
Mycobacterium tuberculosis adaptive response to DNA methylation stress
F. Maria
2015
Corpus ID: 85688879
Tuberculosis (TB) is an infectious disease caused by the micro-organism Mycobacterium tuberculosis (MTB) that currently…
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2012
2012
Alkbh2 protects against lethality and mutation in primary mouse embryonic fibroblasts.
Stephanie L. Nay
,
Dong-Hyun Lee
,
S. Bates
,
T. O'Connor
DNA Repair
2012
Corpus ID: 207147691
2011
2011
Frequent down‐regulation of hABH2 in gastric cancer and its involvement in growth of cancer cells
Wei Gao
,
Leijia Li
,
P. Xu
,
Jingyuan Fang
,
SH Xiao
,
Shengliang Chen
Journal of Gastroenterology and Hepatology
2011
Corpus ID: 38377821
Background and Aim: Methyl or 1, N6‐ethenoadenine base lesions are frequent and highly‐mutagenic or ‐carcinogenic events in…
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Highly Cited
2006
Highly Cited
2006
Mechanistic implications in the Morita-Baylis-Hillman alkylation: isolation and characterization of an intermediate.
M. Krafft
,
T. Haxell
,
Kimberly A. Seibert
,
K. Abboud
Journal of the American Chemical Society
2006
Corpus ID: 30727767
An intermediate phosphonium salt has never been isolated from the Morita-Baylis-Hillman (MBH) reaction. Due to the weakly basic…
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1995
1995
The Use of Heterogeneous Catalysts for Allylic Alkylation
S. Malhotra
1995
Corpus ID: 91744753
Review
1987
Review
1987
Applied heterogeneous catalysis : design, manufacture, use of solid catalysts
J. F. Page
,
J. Limido
,
E. Miller
,
Ryle L. Miller
1987
Corpus ID: 136792943
industrial application of solid acid base catalysts a statistical survey of industrial processes using solid acid base catalysts…
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