Aldolase A
National Institutes of Health
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Cancer metabolic reprogramming promotes tumorigenesis and metastasis, however, the underlying molecular mechanisms are still…
The hypoxia-inducible transcription factor HIF1α drives expression of many glycolytic enzymes. Here, we show that hypoxic…
Cancer cells are critically dependent on glycolysis. Currently, there is no effective pharmacotherapy that exploits this…
Fructose-bisphosphate aldolase A (ALDOA) is a key enzyme in glycolysis and is responsible for catalyzing the reversible…
The Wnt signaling pathway is an evolutionary conserved system, having pivotal roles during animal development. When over…
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL
Nucleic acid-based therapeutics offer significant…
Background: Due to renewed interest in the Warburg effect, glycolytic enzymes have garnered interest as therapeutic targets for…
Hypoxia-inducible factor 1 (HIF-1) activates erythropoietin gene transcription in Hep3B cells subjected to hypoxia. HIF-1…
SummaryMapping of human aldolase A (ALDOA) gene was performed by molecular hybridization techniques using a panel of human-mouse…