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Adrenocorticotropic hormone excess

Known as: ACTH excess 
Overproduction of adrenocorticotropic hormone (ACTH), which generally leads secondarily to overproduction of cortisol by the adrenal cortex. [DDD… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Transcription controls growth, cell kinetics and cholesterol supply to sustain ACTH responses
Chronic ACTH exposure is associated with adrenal hypertrophy and steroidogenesis. The underlying molecular processes in mice have… Expand
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Review
2017
Review
2017
Effects of Chronic ACTH Excess on Human Adrenal Cortex
Chronic ACTH excess leads to chronic cortisol excess, without escape phenomenon, resulting in Cushing's syndrome. Excess adrenal… Expand
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2009
2009
Mineralocorticoid and glucocorticoid receptors stimulate epithelial sodium channel activity in a mouse model of Cushing syndrome.
Experiments in Cushing patients and healthy control subjects receiving adrenocorticotropic hormone (ACTH) indicate that transient… Expand
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Review
2007
Review
2007
Age-specific changes in sex steroid biosynthesis and sex development.
Normal male sex development requires the SRY gene on the Y chromosome, the regression of Müllerian structures via anti-Müllerian… Expand
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2005
2005
Joint synchrony of reciprocal hormonal signaling in human paradigms of both ACTH excess and cortisol depletion.
The hypothalamo-pituitary-adrenal axis is a stress-adaptive neuroendocrine ensemble, in which adrenocorticotropin (ACTH) drives… Expand
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1994
1994
Dissociation of adrenal androgen and cortisol secretion in Cushing's syndrome.
OBJECTIVES While ACTH may modulate adrenal androgen production, there is evidence that other factors are required. Cushing's… Expand
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1983
1983
The origin of plasma deoxycorticosterone in the syndrome of congenital adrenal hyperplasia and in acute states of adrenocorticotropin excess.
Studies in men and women indicate that plasma deoxycorticosterone (DOC) is derived both from direct secretion and also peripheral… Expand
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1977
1977
Plasma pregnenolone and 17-OH-pregnenolone in patients with adrenal tumors, ACTH excess, or idiopathic hirsutism.
Plasma levels of the delta5-pregnenes, pregenolone and 17-OH-pregnenolone, were measured in patients with disordered… Expand
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1971
1971
Diagnosis of adrenal disease by visualization of human adrenal glands with 131 I-19-iodocholesterol.
Abstract Normally functioning adrenal glands in four patients were readily visualized with the Anger camera and a rectilinear… Expand
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1969
1969
Cushing's syndrome and adrenal medullary insufficiency with bilateral adrenal calcification.
ABSTRACT A case study of a 60-yr-old white female with adrenal calcification which preceded the development of Cushing's syndrome… Expand
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