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Adenoviral Vector

Known as: Adenovirus Vector 
One of a number of genetically-engineered adenoviruses designed to insert a gene of interest into a eukaryotic cell where the gene of interest is… 
National Institutes of Health

Papers overview

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Review
2006
Review
2006
HIV vaccines: new frontiers in vaccine development.
A human immunodeficiency virus (HIV) vaccine is the most promising and feasible strategy to prevent the events during acute… 
Highly Cited
2002
Highly Cited
2002
Modulation of Adenovirus Vector Tropism via Incorporation of Polypeptide Ligands into the Fiber Protein
ABSTRACT The efficacy of adenovirus (Ad)-based gene therapy might be significantly improved if viral vectors capable of tissue… 
Highly Cited
2001
Highly Cited
2001
Efficient antigen gene transduction using Arg-Gly-Asp fiber-mutant adenovirus vectors can potentiate antitumor vaccine efficacy and maturation of murine dendritic cells.
Dendritic cells (DCs), the most effective antigen-presenting cells, are being studied as adjuvants or antigen delivery vehicles… 
Highly Cited
1999
Highly Cited
1999
Induction of antitumor immunity with dendritic cells transduced with adenovirus vector-encoding endogenous tumor-associated antigens.
Dendritic cells (DCs) are professional Ag-presenting cells that are being considered as potential immunotherapeutic agents to… 
Highly Cited
1999
Highly Cited
1999
Adenovirus-Mediated p21(WAF1/SDII/CIP1)Gene Transfer Induces Apoptosis of Human Cervical Cancer Cell Lines
ABSTRACT p21(WAF1/SDII/CIP1) (p21) arrests cell growth by inhibiting cyclin-depend kinases. To explore the potential of using p21… 
Highly Cited
1998
Highly Cited
1998
Induction of specific T-cell tolerance by adenovirus-transfected, Fas ligand-producing antigen-presenting cells
A major problem associated with adenovirus gene therapy is the T cell-mediated immune response, which is elicited by inoculation… 
Highly Cited
1996
Highly Cited
1996
Construction of a double recombinant adenovirus vector expressing a heterodimeric cytokine: in vitro and in vivo production of biologically active interleukin-12.
Interleukin-12 (IL-12) is a heterodimeric cytokine that plays an important role in the development of cellular immunity. Clinical… 
Highly Cited
1996
Highly Cited
1996
Role of T cells in inflammation caused by adenovirus vectors in the brain.
In many organs, E1-deleted human adenovirus vectors trigger antiviral T cell responses which limit the duration of vector-encoded… 
Highly Cited
1996
Highly Cited
1996
One-month histologic response of transmyocardial laser channels with molecular intervention.
Highly Cited
1993
Highly Cited
1993
Epitope specificity of H-2Kb-restricted, HSV-1-, and HSV-2-cross-reactive cytotoxic T lymphocyte clones.
HSV-1-specific and HSV-1/HSV-2-cross-reactive H-2Kb-restricted cytotoxic T lymphocyte (CTL) clones were derived from a pool of… 
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