From epidemiological synergy to public health policy and practice: the contribution of other sexually transmitted diseases to sexual transmission of HIV infection.
OBJECTIVES: To review the scientific data on the role of sexually transmitted diseases (STDs) in sexual transmission of HIV infection and discuss the implications of these findings for HIV and STD…
Towards a common definition of global health
Epidemiological Synergy: Interrelationships between Human Immunodeficiency Virus Infection and Other Sexually Transmitted Diseases
- J. Wasserheit
- MedicineSexually Transmitted Diseases
- 1 March 1992
Preliminary data from 83 reports on the impact of HIV infection on STDs suggest that, at a community level, HIV infection may increase the prevalence of some STDs (e.g., genital ulcerative and nonulcerative STDs), and if the same STDs facilitate transmission of HIV, these infections may greatly amplify one another.
Weighing the gold in the gold standard: challenges in HIV prevention research
Almost 90% of HIV prevention trials had ‘flat’ results, which may be attributable to trial design and/or implementation, and the HIV prevention community must not only examine evidence from significant RCTs, but must also examine flat trials and address design and implementation issues that limit detection of an effect.
Combination HIV Prevention: Significance, Challenges, and Opportunities
- A. Kurth, C. Celum, J. Baeten, S. Vermund, J. Wasserheit
- MedicineCurrent HIV/AIDS Reports
- 1 March 2011
There is an unprecedented opportunity to develop “prevention packages” that combine various arrays of evidence-based strategies, tailored to the needs of diverse subgroups and targeted to achieve high coverage for a measurable reduction in population-level HIV transmission.
The emerging threat of untreatable gonococcal infection.
During the past 3 years, the wily gonococcus has become less susceptible to the last line of antimi crobial defense, threatening the ability to cure gonorrhea and prevent severe sequelae.
The dynamic topology of sexually transmitted disease epidemics: implications for prevention strategies.
Each sexually transmitted disease (STD) epidemic evolves through predictable phases, shaped by a dynamic interplay among the pathogen, the behaviors of the subpopulations in which it emerges, and the…
Treatment of sexually transmitted infections for HIV prevention: end of the road or new beginning?
- R. Hayes, D. Watson-Jones, C. Celum, J. H. van de Wijgert, J. Wasserheit
- MedicineAIDS (London)
- 1 October 2010
It is time for a new phase of exploration of how, when, and in whom to include STI control as a key component of HIV prevention, driven by basic research to elucidate the mechanisms by which STIs and vaginal infections facilitate HIV transmission.
Genital chlamydial infections: epidemiology and reproductive sequelae.
The significance and scope of reproductive tract infections among Third World women
- J. Wasserheit
- MedicineSupplement to International journal of gynecology…