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Development of the acute and chronic inflammatory responses known as gout and pseudogout are associated with the deposition of… Expand Salt and drought stress signal transduction consists of ionic and osmotic homeostasis signaling pathways, detoxification (i.e… Expand Lipid homeostasis in vertebrate cells is regulated by a family of membrane-bound transcription factors designated sterol… Expand B and T lymphocytes are the mediators of immunity, but their function is under the control of dendritic cells. Dendritic cells in… Expand The transforming growth factor beta (TGF-beta) family of growth factors control the development and homeostasis of most tissues… Expand The hypothalamus plays a central role in the integrated control of feeding and energy homeostasis. We have identified two novel… Expand NF-kappa B is a ubiquitous transcription factor. Nevertheless, its properties seem to be most extensively exploited in cells of… Expand PROTEIN-protein interactions between two proteins have generally been studied using biochemical techniques such as crosslinking… Expand Protein kinase C has a crucial role in signal transduction for a variety of biologically active substances which activate… Expand There has recently been rapid progress in understanding receptors that generate intracellular signals from inositol lipids. One… Expand