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Acecainide
Known as:
Benzamide, 4-(acetylamino)-N-(2-(diethylamino)ethyl)-
, N Acetylprocainamide
, N-acetylprocainamide
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A major metabolite of PROCAINAMIDE. Its anti-arrhythmic action may cause cardiac toxicity in kidney failure.
National Institutes of Health
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Related topics
Related topics
10 relations
Acecainide Hydrochloride
In Blood
agonists
analogs & derivatives
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Broader (1)
Anti-Arrhythmia Agents
Narrower (1)
desethyl-N-acetylprocainamide
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1993
1993
Procainamide-induced myasthenia-like weakness and dysphagia
Miller Cd
,
Oleshansky Ma
,
Gibson Kf
,
Cantilena Lr
1993
Corpus ID: 71270754
: A 64-year-old man with chronic renal insufficiency was hospitalized with dysphagia and inability to keep his head erect 11…
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1986
1986
Hemoperfusion for treatment of N-acetylprocainamide intoxication.
G. Braden
,
J. Fitzgibbons
,
M. Germain
,
H. M. Ledewitz
Annals of Internal Medicine
1986
Corpus ID: 5849509
Excerpt The pharmacokinetics of procainamide and its major metabolite,N-acetylprocainamide, are significantly altered in patients…
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1983
1983
An HPLC method for the simultaneous quantitation of quinidine, procainamide, N-acetylprocainamide, and disopyramide.
R. R. Bridges
,
T. Jennison
Journal of Analytical Toxicology
1983
Corpus ID: 7377026
A high performance liquid chromatographic method is reported, which incorporates three internal standards (I-cinchonidine, N…
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1982
1982
Ethanol-induced increase in procainamide acetylation in man.
H. Olsen
,
J. Mørland
British Journal of Clinical Pharmacology
1982
Corpus ID: 35452383
1 The effect of ethanol on procainamide pharmacokinetics was studied in humans by two different experimental designs. In one…
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1982
1982
Kinetic Analysis of the Vasodilator and Ganglionic Blocking Actions of N‐Acetylprocainamide
J. R. Eudeikis
,
T. Henthorn
,
J. Lertora
,
A. Atkinson
,
G. Chao
,
W. Kushner
Journal of Cardiovascular Pharmacology
1982
Corpus ID: 527034
Summary The hypotensive effects of N-acetylprocainamide (NAPA) were studied in anesthetized dogs and in a normal subject. In dogs…
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1982
1982
Theophylline, dyphylline, caffeine, acetaminophen, salicylate, acetylsalicylate, procainamide, and N-acetylprocainamide determined in serum with a single liquid-chromatographic assay.
C. Ou
,
V. Frawley
Clinical Chemistry
1982
Corpus ID: 23127319
We describe a single set of liquid-chromatographic conditions for assay of theophylline, dyphylline, caffeine, acetaminophen…
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1981
1981
Determination of procainamide and N-acetylprocainamide by "high-performance" liquid chromatography.
F. M. Stearns
Clinical Chemistry
1981
Corpus ID: 36184140
Frank M. Stearns, Center for Laboratory Medicine, Trevose, PA 19047 Larry A. Broussard, Cunningham Pathology Associates, aka…
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1978
1978
Simultaneous determination of procainamide and N-acetylprocainamide in plasma by high-performance liquid chromatography.
A. G. Butterfield
,
J. K. Cooper
,
K. Midha
Journal of Pharmacy and Science
1978
Corpus ID: 19564266
A sensitive, specific, high-performance liquid chromatographic procedure is described for the simultaneous determination of…
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1977
1977
Determination of plasma procainamide and N-acetylprocainamide concentration by high-pressure liquid chromatography.
J. Dutcher
,
J. Strong
Clinical Chemistry
1977
Corpus ID: 14283670
We describe a routine method for determining concentrations of the antiarrhythmic drug procainamide and its active metabolite, N…
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1975
1975
GLC determination of procainamide in biological fluids.
K. Simons
,
R. Levy
Journal of Pharmacy and Science
1975
Corpus ID: 31528412
A GLC method for the determination of procainamide in biological fluids is presented. By using a dipropyl analog of procainamide…
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