Absence of Biallelic TCRgamma Deletion

Known as: ABD, Absence of Biallelic TCRgamma Locus Deletion 
The absence of rearrangement of at least one allele of the T-cell receptor gamma gene locus. This lack of rearrangement is characteristic of early… (More)
National Institutes of Health

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TRG gene

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2012
2012
Coexpression Network Analysis in Abdominal and Gluteal Adipose Tissue Reveals Regulatory Genetic Loci for Metabolic Syndrome and Related Phenotypes
Metabolic Syndrome (MetS) is highly prevalent and has considerable public health impact, but its underlying genetic factors… (More)
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Highly Cited
2011
Highly Cited
2011
Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases.
Zinc-finger nucleases (ZFNs) are powerful tools for producing gene knockouts (KOs) with high efficiency. Whereas ZFN-mediated… (More)
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2010
2010
Absence of biallelic TCRgamma deletion predicts early treatment failure in pediatric T-cell acute lymphoblastic leukemia.
PURPOSE To identify children with T-cell acute lymphoblastic leukemia (T-ALL) at high risk of induction chemotherapy failure by… (More)
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Highly Cited
2009
Highly Cited
2009
CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing.
Trimethylation of histone H3 lysine 27 (H3K27me3) by Polycomb repressive complex 2 (PRC2) is essential for transcriptional… (More)
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Highly Cited
2005
Highly Cited
2005
The ant subfamily Pseudomyrmecinae (Hymenoptera: Formicidae): phylogeny and evolution of big‐eyed arboreal ants
The ant subfamily Pseudomyrmecinae comprises three genera of hyperoptic, arboreal ants, widely distributed in tropical and… (More)
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Highly Cited
2004
Highly Cited
2004
Functional defects in the fanconi anemia pathway in pancreatic cancer cells.
Biallelic BRCA2-mutations can cause Fanconi anemia and are found in approximately 7% of pancreatic cancers. Recently, several… (More)
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Highly Cited
1998
Highly Cited
1998
Dorsotonals/homothorax, the Drosophila homologue of meis1, interacts with extradenticle in patterning of the embryonic PNS.
The homeotic genes of the bithorax complex are required, among other things, for establishing the patterns of sensory organs in… (More)
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1994
1994
Enhancer point mutation results in a homeotic transformation in Drosophila.
In Drosophila, the misexpression or altered activity of genes from the bithorax complex results in homeotic transformations. One… (More)
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1990
1990
Characterization of two RNAs transcribed from the cis-regulatory region of the abd-A domain within the Drosophila bithorax complex.
The infra-abdominal (iab) regions of the biothorax complex are thought to cis-regulate expression of the abdominal-A (abd-A) and… (More)
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Highly Cited
1990
Highly Cited
1990
Expression and regulation of the abd-A gene of Drosophila.
We have developed a specific polyclonal antibody that recognizes the protein products of the abdominal-A (abd-A) gene, a member… (More)
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