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Genome-scale approaches to resolving incongruence in molecular phylogenies
The results suggest that data sets consisting of single or a small number of concatenated genes have a significant probability of supporting conflicting topologies, and have important implications for resolving branches of the tree of life.
Evo-Devo and an Expanding Evolutionary Synthesis: A Genetic Theory of Morphological Evolution
- S. Carroll
- 11 July 2008
Integration of positional signals and regulation of wing formation and identity by Drosophila vestigial gene
The Drosophila vestigial gene is selectively required for wing-cell proliferation, and is sufficient to induce outgrowths of wing tissue from eyes, legs and antennae.
Regulation of achaete-scute gene expression and sensory organ pattern formation in the Drosophila wing.
This work shows that two positive regulators of sensory neurogenesis, the proneural achaete and scute proteins, initially trans-activate each other and are transiently expressed in identical patterns, including clusters of wing ectodermal cells and the individual sensory mother cells that arise from them.
Endless forms most beautiful : the new science of evo devo and the making of the animal kingdom
- S. Carroll
Evo devo’s methods of illustrating how animal forms evolve offer a much more powerful explanatory vision than the abstract extrapolations of the era of the modern evolutionary synthesis, and allows the deep principles underlying the unity and diversity of life to emerge.
Chance caught on the wing: cis-regulatory evolution and the origin of pigment patterns in Drosophila
It is shown that the evolution of this spot involved modifications of an ancestral cis-regulatory element of the yellow pigmentation gene, which has gained multiple binding sites for transcription factors that are deeply conserved components of the regulatory landscape controlling wing development.
Chance and necessity: the evolution of morphological complexity and diversity
- S. Carroll
- 22 February 2001
Although simple filamentous and spherical forms may evolve wherever cellular life exists, the evolution of motile, modular mega-organisms might not be a universal pattern.
The Development of Crustacean Limbs and the Evolution of Arthropods
Arthropods exhibit great diversity in the position, number, morphology, and function of their limbs. The evolutionary relations among limb types and among the arthropod groups that bear them…
Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic
The results suggest that Dpp signalling regulates gene expression by activating Mad binding to target gene enhancers, which is required for the activation of an enhancer within the vestigial wing-patterning gene in cells across the entire developing wing blade.
Reciprocal functions of the Drosophila yellow and ebony proteins in the development and evolution of pigment patterns.
It is found that Yellow and Ebony are expressed in complementary spatial patterns that correlate with the formation of an evolutionary novel, male-specific pigment pattern in Drosophila biarmipes wings, providing a developmental and genetic framework for understanding the evolution of melanin patterns.