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AZD9496

Known as: AZD 9496, SERD AZD9496, AZD-9496 
An orally available selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon administration, SERD AZD9496 binds to… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

CinnamatesIndoles
NCIt Antineoplastic Agent Terminology

Papers overview

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2020
2020
Development and validation of bioanalytical methods to support investigations of AZD9496 in the clinic.
Aim: AZD9496 is an oral nonsteroidal, potent and selective antagonist and degrader of ER-α. Two major active metabolites (M3 and… 
2015
2015
Abstract 3650: Discovery of the clinical candidate AZD9496: a potent and orally bioavailable selective estrogen receptor downregulator and antagonist
Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA With over 70% of breast cancers expressing the… 
2015
2015
Abstract DDT01-03: Discovery and pre-clinical pharmacology of AZD9496: An oral, selective estrogen receptor down-regulator (SERD)
With over 70% of breast cancers expressing estrogen receptor alpha protein (ERα), treatment with either anti-hormonal therapies… 
2013
2013
The role of heterotrophic microorganism Galactomyces sp. Z3 in improving pig slurry bioleaching
The feasibility of removing heavy metals and eliminating pathogens from pig slurry through bioleaching involving the fungus… 
2010
2010
Étude des frottements internes dans le tellurure de bismuth préparé par extrusion
Dans ce travail nous avons realise au laboratoire un montage experimental qui permet l’etude, en fonction de la temperature, des… 
2004
2004
Soil microbial population dynamics following bioaugmentation with a 3-chlorobenzoate-degrading bacterial culture
Changes in microbial populations were evaluated following inoculation of contaminated soil with a 3-chlorobenzoate degrader… 
1999
1999
Effect of novel biosurfactants on biodegradation of polychlorinated biphenyls by pure and mixed bacterial cultures.
A study was conducted to determine the potential positive effect of novel biosurfactants on the enhancement of Aroclor 1248… 
1998
1998
Ensemencement mixte de moût avec des levures Saccharomyces et non-Saccharomyces : incidence sur l'acidité et les arômes fermentaires des vins
Au cours de la fermentation des mouts, un grand nombre d'especes differentes de levures peut etre mis en evidence (1) (2) (3) (4… 
Review
1994
Review
1994
Role of distal splenorenal shunt for long-term management of variceal bleeding
Distal splenorenal shunt (DSRS) has been studied extensively over the past 25 years to define its role in management of variceal… 
1989
1989
Microbial degradation of some soil-applied insecticides, herbicides, and insecticide-herbicide combinations
Cette etude a pour but de montrer si des populations de microorganismes du sol adaptees pour la degradation acceleree d'un type… 
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