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AZD7325

National Institutes of Health

Papers overview

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Review
2020
Review
2020
Abstract GABA (γ-amino butyric acid) is an important inhibitory neurotransmitter in the central nervous system. Attenuation of… Expand
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2018
2018
Fast inhibitory synaptic transmission is mediated by γ-aminobutyric acid type A receptors (GABAARs) that are enriched at… Expand
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2018
2018
AZD7325 [4-amino-8-(2-fluoro-6-methoxyphenyl)-N-propylcinnoline-3-carboxamide] is a selective GABAAα2,3 receptor modulator… Expand
2018
2018
Abstract Anxiolytic activity has been associated with GABAA α2 and α3 subunits. Several target compounds were identified and… Expand
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2016
2016
Exploring drug targets based on disease-associated molecular mechanisms during development is crucial for the generation of novel… Expand
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2016
2016
RationaleSedation, dependence, and abuse liability limit the use of non-selective γ-aminobutyric acid (GABAA) receptor positive… Expand
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2015
2015
Compounds with selectivity for GABAA receptor subtypes may differ significantly from nonselective benzodiazepines in their… Expand
2014
2014
AIMS AZD7325 is a novel α2,3 -subtype-selective partial GABA-A-receptor modulator. This study investigated the pharmacodynamics… Expand
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2014
2014
AZD7325 is a selective gamma‐amino‐butyric acid (GABAA)α2, 3 receptor modulator. The aims of this analysis were to develop… Expand
2012
2012
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • AZD7325 is an orally administered, potent, selective gamma-amino-butyric acid (GABA(A… Expand
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