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AZD2171

Known as: AZD 2171, AZD-2171, AZD2171 Maleate 
An indole ether quinazoline derivative with antineoplastic properties. Competing with adenosine triphosphate, AZD2171 binds to and inhibits all three… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND Poly(ADP-ribose) polymerase (PARP)-inhibitors and anti-angiogenics have activity in recurrent ovarian and breast… Expand
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2009
2009
PurposeCediranib (recentin, AZD2171) is an oral small-molecule multiple receptor tyrosine kinases inhibitor. Here we investigate… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Inhibition of vascular endothelial growth factor mediated signaling shows promise as an antiangiogenic strategy for… Expand
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Review
2008
Review
2008
The mechanisms involved in the epithelial to mesenchymal transition (EMT) are integrated in concert with master developmental and… Expand
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2008
2008
PURPOSE Inhibition of vascular endothelial growth factor-A (VEGF) signaling is a key therapeutic approach in oncology given the… Expand
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Highly Cited
2007
Highly Cited
2007
Using MRI techniques, we show here that normalization of tumor vessels in recurrent glioblastoma patients by daily administration… Expand
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Highly Cited
2007
Highly Cited
2007
PURPOSE AZD2171 is a highly potent oral selective inhibitor of vascular endothelial growth factor (VEGF) signaling. This phase I… Expand
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Highly Cited
2007
Highly Cited
2007
PURPOSE AZD2171 is an oral, highly potent, and selective vascular endothelial growth factor signaling inhibitor that inhibits all… Expand
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Highly Cited
2005
Highly Cited
2005
Inhibition of vascular endothelial growth factor-A (VEGF) signaling is a promising therapeutic approach that aims to stabilize… Expand
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