Recentin
National Institutes of Health
Papers overview
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PURPOSE
Cediranib is a highly potent inhibitor of vascular endothelial growth factor (VEGF) signaling with activity against all…
PurposeCediranib (recentin, AZD2171) is an oral small-molecule multiple receptor tyrosine kinases inhibitor. Here we investigate…
PurposeTo evaluate safety and tolerability of cediranib, a highly potent and selective vascular endothelial growth factor…
Brain metastasis has become an increasing cause of morbidity and mortality in cancer patients as the treatment of systemic…
Angiogenesis, the process whereby tumors develop new blood vessels to facilitate growth and metastasis, is a pivotal event in…
Purpose: Inhibition of vascular endothelial growth factor-A (VEGF) signaling is a key therapeutic approach in oncology given the…
Solid tumors express a range of factors required to sustain their growth and promote their dissemination. Among these are…
A number of pre-clinical studies have suggested that blocking vascular endothelial growth factor (VEGF) signalling can be…