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AZD 1305

Known as: AZD-1305, AZD1305 
National Institutes of Health

Papers overview

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2016
2016
PKPD modelling of PR and QRS intervals in conscious dogs using standard safety pharmacology data.
2013
2013
Vernakalant is devoid of proarrhythmic effects in the complete AV block dog model.
2012
2012
Preformulation evaluation of AZD1305, an oxabispidine intended for oral and intravenous treatment
Aim: AZD1305 is a novel, water-soluble investigational antiarrhythmic agent for restoration and maintenance of sinus rhythm in… 
2010
2010
AZD1305 Exerts Atrial Predominant Electrophysiological Actions and Is Effective in Suppressing Atrial Fibrillation and Preventing Its Reinduction in the Dog
Recent development of drugs for the treatment of atrial fibrillation (AF) has focused on atrial selective agents. We examined the… 
2010
2010
Electrophysiologic and Antiarrhythmic Effects of AZD1305 in Canine Pulmonary Vein Sleeves
The objective of this study was to examine the electrophysiologic and antiarrhythmic effects of the new antiarrhythmic agent tert… 
2010
2010
The combined ion channel blocker AZD1305 attenuates late Na current and IKr-induced action potential prolongation and repolarization instability.
AIMS To assess the late Na+ current (INalate) blockade by the combined ion channel blocker AZD1305 and its influence on… 
2010
2010
A Randomized Invasive Cardiac Electrophysiology Study of the Combined Ion Channel Blocker AZD1305 in Patients After Catheter Ablation of Atrial Flutter
Background: This study assessed the cardiac electrophysiological and hemodynamic effects of an intravenous infusion of the… 
2009
2009
Rapid Conversion of Persistent Atrial Fibrillation to Sinus Rhythm by Intravenous AZD7009
This randomized, double‐blind trial compared cardioversion rates between AZD7009 infusion (15‐minute 3.25 mg/min, 15‐minute 4.4… 
2009
2009
AZD1305 has Atrial-Predominant Electrophysiologic Actions and is Effective in Suppressing Atrial Fibrillation in the Dog
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