AZ10606120

 
National Institutes of Health

Papers overview

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2017
2017
The P2X7 receptor (P2X7R) for ATP is a therapeutic target for pathophysiological states including inflammation, pain management… (More)
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2016
2016
The ATP-gated receptor P2X7 (P2X7R) is involved in regulation of cell survival and has been of interest in cancer field… (More)
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2015
2015
BackgroundPancreatic ductal adenocarcinoma (PDAC) is presently one of the cancers with the worst survival rates and least… (More)
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2015
2015
Neuroblastoma (NB) is an aggressive pediatric tumor, responsible for 15% of cancer-related deaths in childhood, lacking an… (More)
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Highly Cited
2014
Highly Cited
2014
As adenosine 5'-triphosphate (ATP) released from astrocytes can modulate many neural signaling systems, the triggers and pathways… (More)
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2014
2014
P2X7 is a purinergic receptor-channel; its activation by ATP elicits a broad set of cellular actions, from apoptosis to signals… (More)
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2014
2014
Purinergic control of vascular tone in the CNS has been largely unexplored. This study examines the contribution of endogenous… (More)
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2013
2013
The P2X7 purinergic receptor is a ligand-gated cation channel expressed on leukocytes including microglia. This study aimed to… (More)
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2012
2012
The pancreatic stellate cells (PSCs) have complex roles in pancreas, including tissue repair and fibrosis. PSCs surround ATP… (More)
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2010
2010
The P2X7 receptor is a trimeric channel with three binding sites for ATP, but how the occupancy of these sites affects gating is… (More)
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