FAQ

AXL gene

Known as: JTK11, AXL TRANSFORMING GENE, Tyro7 
This gene plays a role in the tyrosine kinase receptor-mediated signal transduction pathway. The gene is also involved in cellular proliferation and… (More)

Topic mentions per year

Topic mentions per year

1935-2018
0204019352017

Related topics

Related topics

10 relations
AXL protein, humanAXL wt AlleleCell ProliferationLigand Binding
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
AXL gene
leukemia
Signal Transduction
Cell Proliferation
Receptor Signaling
Phosphorylation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Expression Analysis Highlights AXL as a Candidate Zika Virus Entry Receptor in Neural Stem Cells.
The recent outbreak of Zika virus (ZIKV) in Brazil has been linked to substantial increases in fetal abnormalities and… (More)
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Highly Cited
2008
Highly Cited
2008
AXL is a potential target for therapeutic intervention in breast cancer progression.
Protein kinases play important roles in tumor development and progression. A variety of members of this family of signal… (More)
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Highly Cited
1996
Highly Cited
1996
Activation of beta-adrenergic receptor kinase during myocardial ischemia.
During myocardial ischemia, a local release of noradrenaline coincides with an increased density of beta-adrenergic receptors… (More)
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Highly Cited
1995
Highly Cited
1995
Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor.
Transgenic mice were created with cardiac-specific overexpression of the beta-adrenergic receptor kinase-1 (beta ARK1) or a beta… (More)
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Highly Cited
1994
Highly Cited
1994
Expression of beta-arrestins and beta-adrenergic receptor kinases in the failing human heart.
The beta-adrenergic receptor system of the failing human heart is markedly desensitized. We have recently postulated that this… (More)
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Highly Cited
1993
Highly Cited
1993
Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart.
BACKGROUND In chronic heart failure, the positive inotropic effects of beta-adrenergic receptor agonists are greatly reduced, in… (More)
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Highly Cited
1993
Highly Cited
1993
The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase.
The beta gamma subunits of heterotrimeric G proteins play important roles in regulating receptor-stimulated signal transduction… (More)
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Highly Cited
1992
Highly Cited
1992
Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors.
The rate and extent of the agonist-dependent phosphorylation of beta 2-adrenergic receptors and rhodopsin by beta-adrenergic… (More)
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Highly Cited
1992
Highly Cited
1992
Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family.
Homologous or agonist-specific desensitization of beta 2-adrenergic receptors (beta 2AR) is mediated by the beta-adrenergic… (More)
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Highly Cited
1990
Highly Cited
1990
beta-Arrestin: a protein that regulates beta-adrenergic receptor function.
Homologous or agonist-specific desensitization of beta-adrenergic receptors is thought to be mediated by a specific kinase, the… (More)
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