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AXIN2 gene

Known as: MGC126582, Axin 2 Gene, conductin 
This gene is involved in signal transduction and plays a role in development.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
The source of new hepatocytes in the uninjured liver has remained an open question. By lineage tracing using the Wnt-responsive… Expand
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Highly Cited
2004
Highly Cited
2004
Wnt signaling regulates embryonic pattern formation and morphogenesis of most organs. Aberrations of regulation of Wnt signaling… Expand
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Highly Cited
2004
Highly Cited
2004
Aberrant WNT pathway signaling is an early progression event in 90% of colorectal cancers. It occurs through mutations mainly of… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT Axin2/Conductin/Axil and its ortholog Axin are negative regulators of the Wnt signaling pathway, which promote the… Expand
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Highly Cited
2002
Highly Cited
2002
The transactivation of TCF target genes induced by Wnt pathway mutations constitutes the primary transforming event in colorectal… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT Activation of Wnt signaling through β-catenin/TCF complexes is a key event in the development of various tumors, in… Expand
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Highly Cited
2002
Highly Cited
2002
Activation of Wnt signaling through β-catenin mutations contributes to the development of hepatocellular carcinoma (HCC) and… Expand
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Highly Cited
2002
Highly Cited
2002
The Wnt pathway regulates cell fate, proliferation, and apoptosis, and defects in the pathway play a key role in many cancers… Expand
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Review
1999
Review
1999
  • P. Morin
  • BioEssays : news and reviews in molecular…
  • 1999
  • Corpus ID: 33660494
Since its discovery as a protein associated with the cytoplasmic region of E-cadherin, beta-catenin has been shown to perform two… Expand
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Highly Cited
1998
Highly Cited
1998
Control of stability of beta-catenin is central in the wnt signaling pathway. Here, the protein conductin was found to form a… Expand
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