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AXIN2 gene

Known as: MGC126582, Axin 2 Gene, conductin 
This gene is involved in signal transduction and plays a role in development.
National Institutes of Health

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6 relations
AXIN2 protein, humanBreast CarcinomaColorectal CarcinomaNeuroblastoma

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AXIN2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
The association between three AXIN2 variants and cancer risk
Plenty of epidemiological studies have assessed the effects of AXIN2 polymorphisms on the risk of developing cancer, but the… 
2018
2018
miR-3120-5p promotes colon cancer stem cell stemness and invasiveness through targeting Axin2.
2015
2015
Wnt ligand–dependent activation of the negative feedback regulator Nkd1
Nkd1, a negative feedback regulator of the Wnt pathway, localizes with Dvl2 to the putative Wnt signalosome, where it becomes… 
Highly Cited
2013
Highly Cited
2013
Regulation of APC and AXIN2 expression by intestinal tumor suppressor CDX2 in colon cancer cells.
Wnt signaling is often constitutively active in colorectal cancer cells. The expression of the intestinal specific transcription… 
2013
2013
Expression and localization of axin 2 in colorectal carcinoma and its clinical implication
PurposeAberrant activation of the Wnt/β-catenin pathway plays a major role in the development of colorectal carcinoma (CRC). Axin… 
2008
2008
Mutations in components of the Wnt signaling pathway in gastric cancer.
AIM To explore the contribution of AXIN1, AXIN2 and beta-catenin, components of Wnt signaling pathway, to the carcinogenesis of… 
Highly Cited
2008
Highly Cited
2008
Association of Genetic Variation in Genes Implicated in the β-Catenin Destruction Complex with Risk of Breast Cancer
Aberrant Wnt/β-catenin signaling leading to nuclear accumulation of the oncogene product β-catenin is observed in a wide spectrum… 
2008
2008
Axin2 expression identifies progenitor cells in the murine prostate
We previously reported that prostatic stem/progenitor cells are concentrated in the proximal region of prostatic ducts and… 
Highly Cited
2007
Highly Cited
2007
Craniosynostosis caused by Axin2 deficiency is mediated through distinct functions of beta-catenin in proliferation and differentiation.
1954
1954
Studies on the Heat Conductin in Wood : The present study is a discussion on the results of investigations made hitherto by author on heat conduction in wood.
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