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ATXN2 protein, human

Known as: ataxin-2 protein, human, Spinocerebellar Ataxia Type 2 Protein, ATX2 protein, human 
Ataxin-2 (1313 aa, ~140 kDa) is encoded by the human ATXN2 gene. This protein plays a role in the modulation of epidermal growth factor receptor… 
National Institutes of Health

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Related topics

9 relations
ATXN2 geneCellular MembraneCytoplasmLigand Binding

Broader (1)

Ataxin-2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Intermediate-length polyglutamine in ATXN2 is a possible risk factor among Eastern Chinese patients with amyotrophic lateral sclerosis
2014
2014
Neuropathological Staging of Spinocerebellar Ataxia Type 2 by Semiquantitative 1C2‐Positive Neuron Typing. Nuclear Translocation of Cytoplasmic 1C2 Underlies Disease Progression of Spinocerebellar…
Spinocerebellar ataxia type 2 (SCA2) is a hereditary neurodegenerative disorder caused by the expansion of the trinucleotide CAG… 
2007
2007
Gene expression in opening and senescing petals of morning glory (Ipomoea nil) flowers
We isolated several senescence-associated genes (SAGs) from the petals of morning glory (Ipomoea nil) flowers, with the aim of… 
2007
2007
INCLUSION FORMATION BY ATAXINS -1, -2, -3, AND -7
The authors studied inclusion formation in vitro using transiently transfected PC12 cells, with epitope-tagged and untagged full… 
2005
2005
Relative Atrophy of the Flocculus and Ocular Motor Dysfunction in SCA2 and SCA6
Abstract: Two hereditary ataxia syndromes show distinct profiles of region‐specific atrophy and ocular motor deficits. Selective… 
2004
2004
Can ataxin-2 be down-regulated by allele-specific de novo DNA methylation in SCA2 patients?
Highly Cited
2003
Highly Cited
2003
The gene for HMSN2C maps to 12q23-24
Background: Hereditary motor and sensory neuropathy type 2C (HMSN2C, Charcot–Marie–Tooth 2C [CMT2C]) is an autosomal dominant… 
2002
2002
Accurate determination of ataxin-2 polyglutamine expansion in patients with intermediate-range repeats.
Spinocerebellar ataxia, type 2 (SCA2), results from an expansion of a stretch of polyglutamine repeats within the coding sequence… 
Highly Cited
2001
Highly Cited
2001
Amino acid sequences flanking polyglutamine stretches influence their potential for aggregate formation
Expanded polyglutamine stretches have been shown to form aggregates and to be toxic to cells. In this study, we hypothesized that… 
2001
2001
Localization of ataxin-2 within the cerebellar cortex of the rat
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