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ATP7A gene

Known as: ATPase copper transporting alpha, ATPase, Cu++ Transporting, Alpha Polypeptide (Menkes Syndrome) Gene, copper-transporting ATPase 1 
This gene is involved in copper transport.
National Institutes of Health

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9 relations
ATP HydrolysisATP7A protein, humanCopper-Transporting ATPase 1Homo sapiens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Identification of novel ATP7A mutations and prenatal diagnosis in Chinese patients with Menkes disease
Menkes disease (MD) is a fatal X-linked multisystem disease caused by mutations in ATP7A. In this study, clinical and genetic… 
2015
2015
X‐linked spinal muscular atrophy in mice caused by autonomous loss of ATP7A in the motor neuron
ATP7A is a copper‐transporting P‐type ATPase that is essential for cellular copper homeostasis. Loss‐of‐function mutations in the… 
Review
2015
Review
2015
Is It a Pathogenic ATP7A Variation and Is It Menkes Disease?
This paper is a comment on “Menkes Disease Presenting with Epilepsia Partialis Continua.” While updating the LOVD (Leiden Open… 
2014
2014
ATP7A trafficking and mechanisms underlying the distal motor neuropathy induced by mutations in ATP7A
Diverse mutations in the gene encoding the copper transporter ATP7A lead to X‐linked recessive Menkes disease or occipital horn… 
Highly Cited
2014
Highly Cited
2014
miR‐495 Enhances the Sensitivity of Non‐Small Cell Lung Cancer Cells to Platinum by Modulation of Copper‐Transporting P‐type Adenosine Triphosphatase A (ATP7A)
Copper‐transporting P‐type adenosine triphosphatase A (ATP7A) is associated with platinum drug resistance in non‐small cell lung… 
2014
2014
Annexin A4‐conferred platinum resistance is mediated by the copper transporter ATP7A
Although platinum drugs are often used for the chemotherapy of human cancers, platinum resistance is a major issue and may… 
2013
2013
Production of LPS-induced inflammatory mediators in murine peritoneal macrophages: neocuproine as a broad inhibitor and ATP7A as a selective regulator
Copper chelation regulates the production of inflammatory mediators in vivo during vascular inflammation and atherogenesis… 
2013
2013
A silent nucleotide substitution in the ATP7A gene in a child with Menkes disease.
2010
2010
Role of Glutaredoxin 1 and Glutathione in Regulating the Activity of the Copper-transporting P-type ATPases , ATP 7 A and ATP 7 B *
From the Strategic Research Centre for Molecular and Medical Research and Centre for Cellular and Molecular Biology, School of… 
2008
2008
Mutation Detection in the Menkes Gene ATP7A Using the Protein Truncation Test
Menkes disease (MD) is a rare recessively inherited lethal disorder of copper metabolism. The gene ATP7A defective in MD consists… 
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