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ATP2C2 wt Allele

Known as: Secretory Pathway Calcium ATPase 2 Gene, DKFZp686H22230, ATPase, Ca++ Transporting, Type 2C, Member 2 wt Allele 
Human ATP2C2 wild-type allele is located in the vicinity of 16q24.1 and is approximately 96 kb in length. This allele, which encodes calcium… Expand
National Institutes of Health

Related topics

Related topics

9 relations
16q24.1ATP HydrolysisCalcium BindingHomo sapiens
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Broader (1)

ATP2C2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Manganese and the brain.
Manganese (Mn) is an essential trace metal that is pivotal for normal cell function and metabolism. Its homeostasis is tightly… Expand
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Highly Cited
2013
Highly Cited
2013
SPCA2 Regulates Orai1 Trafficking and Store Independent Ca2+ Entry in a Model of Lactation
An unconventional interaction between SPCA2, an isoform of the Golgi secretory pathway Ca2+-ATPase, and the Ca2+ influx channel… Expand
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Highly Cited
2010
Highly Cited
2010
Store-Independent Activation of Orai1 by SPCA2 in Mammary Tumors
Ca(2+) is an essential and ubiquitous second messenger. Changes in cytosolic Ca(2+) trigger events critical for tumorigenesis… Expand
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Review
2009
Review
2009
Intracellular Ca2+- and Mn2+-transport ATPases.
3.4.3. Artemisinin L 4. SPCAs L 4.1. Genes Encoding SPCAs L 4.2. Structure of SPCAs M 4.2.1. Mn2+ and Ca2+ Binding M 4.2.2… Expand
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Highly Cited
2009
Highly Cited
2009
Mammary gland involution is associated with rapid down regulation of major mammary Ca2+-ATPases.
Sixty percent of calcium in milk is transported across the mammary cells apical membrane by the plasma membrane Ca(2+)-ATPase 2… Expand
Highly Cited
2008
Highly Cited
2008
Hepatic cirrhosis, dystonia, polycythaemia and hypermanganesaemia—A new metabolic disorder
SummaryWe report a new constellation of clinical features consisting of hypermanganesaemia, liver cirrhosis, an extrapyramidal… Expand
Highly Cited
2006
Highly Cited
2006
Dissection of the Functional Differences between Human Secretory Pathway Ca2+/Mn2+-ATPase (SPCA) 1 and 2 Isoenzymes by Steady-state and Transient Kinetic Analyses*
Human secretory pathway Ca2+/Mn2+-ATPase (SPCA) 2 encoded by ATP2C2 is only expressed in a limited number of tissues, unlike the… Expand
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Highly Cited
2005
Highly Cited
2005
A Novel Isoform of the Secretory Pathway Ca2+,Mn2+-ATPase, hSPCA2, Has Unusual Properties and Is Expressed in the Brain*
Unlike lower eukaryotes, mammalian genomes have a second gene, ATP2C2, encoding a putative member of the family of secretory… Expand
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Highly Cited
2005
Highly Cited
2005
The Secretory Pathway Ca2+/Mn2+-ATPase 2 Is a Golgi-localized Pump with High Affinity for Ca2+ Ions*
Accumulation of Ca2+ into the Golgi apparatus is mediated by sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs) and by secretory… Expand
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1998
1998
A Comparative Study of Principal Component Analysis Techniques
Principal Component Analysis (PCA) is a useful technique for reducing the dimensionality of datasets for compression or… Expand
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