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ATP-Binding Cassette Transporters

Known as: ATP Binding Cassette Transporters, ABC Transport Protein, Transporters, ABC 
A family of transmembrane proteins that usually function as dimers to hydrolyze ATP, which permits them to transport a wide variety of substrates… 
National Institutes of Health

Related topics

Related topics

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Narrower (33)

ABCC13 pseudogene, humanABCD1 protein, humanAbcb11 protein, ratAlgS protein, Sphingomonas
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Adenosine TriphosphatasesAdrenoleukodystrophyCellular MembraneDrug Efflux
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
ATP-binding cassette transporters in reproduction: a new frontier.
BACKGROUND The transmembrane ATP-binding cassette (ABC) transporters actively efflux an array of clinically relevant compounds… 
Review
2016
Review
2016
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family in multidrug resistance: A review of the past decade.
Review
2016
Review
2016
Plant ABC Transporters Enable Many Unique Aspects of a Terrestrial Plant's Lifestyle.
Highly Cited
2012
Highly Cited
2012
Pharmacologic inhibition of MALT1 protease by phenothiazines as a therapeutic approach for the treatment of aggressive ABC-DLBCL.
Highly Cited
2011
Highly Cited
2011
Oncogenically active MYD88 mutations in human lymphoma
The activated B-cell-like (ABC) subtype of diffuse large B-cell lymphoma (DLBCL) remains the least curable form of this… 
Highly Cited
2011
Highly Cited
2011
Bacitracin and nisin resistance in Staphylococcus aureus: a novel pathway involving the BraS/BraR two‐component system (SA2417/SA2418) and both the BraD/BraE and VraD/VraE ABC transporters
Two‐component systems (TCSs) are key regulatory pathways allowing bacteria to adapt their genetic expression to environmental… 
Highly Cited
2010
Highly Cited
2010
Broad Conservation of Milk Utilization Genes in Bifidobacterium longum subsp. infantis as Revealed by Comparative Genomic Hybridization
ABSTRACT Human milk oligosaccharides (HMOs) are the third-largest solid component of milk. Their structural complexity renders… 
Highly Cited
2003
Highly Cited
2003
Evidence for Two Interacting Ligand Binding Sites in Human Multidrug Resistance Protein 2 (ATP Binding Cassette C2)*
Multidrug resistance protein 2 (MRP2) belongs to the ATP binding cassette family of transporters. Its substrates include organic… 
Review
2001
Review
2001
The human ATP-binding cassette (ABC) transporter superfamily.
The ATP-binding cassette (ABC) transporter superfamily contains membrane proteins that translocate a variety of substrates across… 
Highly Cited
1998
Highly Cited
1998
ATPase and Multidrug Transport Activities of the Overexpressed Yeast ABC Protein Yor1p*
The Saccharomyces cerevisiae genome encodes 15 full-size ATPbinding cassette transporters (ABC), of whichPDR5, SNQ2, and YOR1 are… 
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