ATP-Binding Cassette Transporters

Known as: ATP Binding Cassette Transporters, ABC Transport Protein, Transporters, ABC 
A family of transmembrane proteins that usually function as dimers to hydrolyze ATP, which permits them to transport a wide variety of substrates… (More)
National Institutes of Health

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Narrower (33)

ABCB6 protein, humanABCC11 protein, humanABCC13 pseudogene, humanABCD1 protein, human
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Adenosine TriphosphatasesAdrenoleukodystrophyCellular MembraneDrug Efflux
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Papers overview

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2014
2014
Nrf2 upregulates ATP binding cassette transporter expression and activity at the blood-brain and blood-spinal cord barriers.
Activation of nuclear factor E2-related factor-2 (Nrf2), a sensor of oxidative stress, is neuroprotective in animal models of… (More)
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2014
2014
ATP-binding cassette transporters P-glycoprotein and breast cancer related protein are reduced in capillary cerebral amyloid angiopathy
Alzheimer's disease (AD) is the most common form of dementia and marked by deposition of amyloid-β (Aβ) within the brain… (More)
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2014
2014
Decreased radixin function for ATP-binding cassette transporters in liver in adjuvant-induced arthritis rats.
Pathophysiological changes are associated with alterations in the expression and function of numerous ADME-related proteins. We… (More)
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Review
2013
Review
2013
ATP-binding cassette transporters and cholesterol translocation.
Cholesterol, a major component of mammalian cell membranes, plays important structural and functional roles. However… (More)
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2012
2012
Influence of ATP-Binding Cassette Transporters in Root Exudation of Phytoalexins, Signals, and in Disease Resistance
The roots of plants secrete compounds as a way to exchange information with organisms living in the soil. Here, we report the… (More)
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Highly Cited
2011
Highly Cited
2011
Oncogenically active MYD88 mutations in human lymphoma
The activated B-cell-like (ABC) subtype of diffuse large B-cell lymphoma (DLBCL) remains the least curable form of this… (More)
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Highly Cited
2010
Highly Cited
2010
Broad conservation of milk utilization genes in Bifidobacterium longum subsp. infantis as revealed by comparative genomic hybridization.
Human milk oligosaccharides (HMOs) are the third-largest solid component of milk. Their structural complexity renders them… (More)
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Highly Cited
2003
Highly Cited
2003
Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2).
Multidrug resistance protein 2 (MRP2) belongs to the ATP binding cassette family of transporters. Its substrates include organic… (More)
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Highly Cited
2001
Highly Cited
2001
Sugar transport in Sulfolobus solfataricus is mediated by two families of binding protein-dependent ABC transporters.
The extreme thermoacidophilic archaeon Sulfolobus solfataricus grows optimally at 80 degrees C and pH 3 and uses a variety of… (More)
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2001
2001
Characterization and functional analysis of the nucleotide binding fold in human peroxisomal ATP binding cassette transporters.
The 70-kDa peroxisomal membrane protein (PMP70) and the adrenoleukodystrophy protein (ALDP) are half ATP binding cassette (ABC… (More)
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