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ATP-Binding Cassette Transporters

Known as: ATP Binding Cassette Transporters, ABC Transport Protein, Transporters, ABC 
A family of transmembrane proteins that usually function as dimers to hydrolyze ATP, which permits them to transport a wide variety of substrates… Expand
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (33)

ABCC13 pseudogene, humanABCD1 protein, humanAbcb11 protein, ratAlgS protein, Sphingomonas
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Adenosine TriphosphatasesAdrenoleukodystrophyCellular MembraneDrug Efflux
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Papers overview

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Review
2016
Review
2016
Plant ABC Transporters Enable Many Unique Aspects of a Terrestrial Plant's Lifestyle.
Terrestrial plants have two to four times more ATP-binding cassette (ABC) transporter genes than other organisms, including their… Expand
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Highly Cited
2014
Highly Cited
2014
Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors
Significance The activated B-cell–like (ABC) subtype of diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer that can… Expand
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Highly Cited
2012
Highly Cited
2012
Pharmacologic inhibition of MALT1 protease by phenothiazines as a therapeutic approach for the treatment of aggressive ABC-DLBCL.
Proteolytic activity of the mucosa-associated lymphoid tissue lymphoma translocation protein-1 (MALT1) paracaspase is required… Expand
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Highly Cited
2011
Highly Cited
2011
Oncogenically active MYD88 mutations in human lymphoma
The activated B-cell-like (ABC) subtype of diffuse large B-cell lymphoma (DLBCL) remains the least curable form of this… Expand
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Highly Cited
2011
Highly Cited
2011
Bacitracin and nisin resistance in Staphylococcus aureus: a novel pathway involving the BraS/BraR two‐component system (SA2417/SA2418) and both the BraD/BraE and VraD/VraE ABC transporters
Two‐component systems (TCSs) are key regulatory pathways allowing bacteria to adapt their genetic expression to environmental… Expand
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Highly Cited
2010
Highly Cited
2010
Broad Conservation of Milk Utilization Genes in Bifidobacterium longum subsp. infantis as Revealed by Comparative Genomic Hybridization
ABSTRACT Human milk oligosaccharides (HMOs) are the third-largest solid component of milk. Their structural complexity renders… Expand
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Highly Cited
2010
Highly Cited
2010
Critical role of PI3K signaling for NF-κB–dependent survival in a subset of activated B-cell–like diffuse large B-cell lymphoma cells
The activated B-cell–like (ABC) subtype of diffuse large B-cell lymphoma (DLBCL) represents a very aggressive human lymphoma… Expand
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Highly Cited
2003
Highly Cited
2003
Evidence for Two Interacting Ligand Binding Sites in Human Multidrug Resistance Protein 2 (ATP Binding Cassette C2)*
Multidrug resistance protein 2 (MRP2) belongs to the ATP binding cassette family of transporters. Its substrates include organic… Expand
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Highly Cited
2001
Highly Cited
2001
Sugar transport in Sulfolobus solfataricus is mediated by two families of binding protein‐dependent ABC transporters
The extreme thermoacidophilic archaeon Sulfolobus solfataricus grows optimally at 80°C and pH 3 and uses a variety of sugars as… Expand
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Highly Cited
1998
Highly Cited
1998
ATPase and Multidrug Transport Activities of the Overexpressed Yeast ABC Protein Yor1p*
The Saccharomyces cerevisiae genome encodes 15 full-size ATPbinding cassette transporters (ABC), of whichPDR5, SNQ2, and YOR1 are… Expand
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