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ATP Binding Cassette Transporter, Sub-Family G, Member 2

Known as: ABCG2 Protein, ATP Binding Cassette Transporter, Sub-Family G, Member 2 [Chemical/Ingredient], Antigen, CD338 
An ATP binding cassette transporter, sub-family G protein that functions as a high capacity UREA exporter, transporter of STEROLS, and in the… 
National Institutes of Health

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ABCG2 protein, humanAbcg2 protein, rat
In BloodProcess of secretionagonistsantagonists & inhibitors

Papers overview

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2019
2019
Abstract 3814: Overcoming multidrug resistance (MDR) in colorectal cancer by modulating exosome-mediated transfer of MDR transporter regulatory machineries
Aim: The study aims to investigate the circumvention of multidrug resistance (MDR) in colorectal cancer by modulating exosome… 
2017
2017
Correlation between clinical response to sorafenib in hepatocellular carcinoma treatment and polymorphisms of P-glycoprotein (ABCB1) and of breast cancer resistance protein (ABCG2): monocentric study
ObjectivesWe studied the relation between the polymorphism of P-glycoprotein (P-gp) and of breast cancer resistance protein (BCRP… 
2017
2017
EXAMINATION OF ABCG2 G34A GENE POLYMORPHISM IN BREAST CANCER PATIENTS
ABCG2 is a half ATP-binding cassette (ABC) transporter that localizes to plasma membranes. It functions as energy-dependent… 
2015
2015
Concurrent effects of ABCB1 C3435T, ABCG2 C421A, and XRCC1 Arg194Trp genetic polymorphisms with risk of cancer, clinical output, and response to treatment with imatinib mesylate in patients with…
There are a paucity and contradicted data about the impact of concurrent heredity of polymorphic genes and risk of chronic… 
2014
2014
WHI-P154 enhances the chemotherapeutic effect of anticancer agents in ABCG2-overexpressing cells
ATP‐binding cassette (ABC) transmembrane proteins evidently decrease the intracellular accumulation of substrate chemotherapeutic… 
2014
2014
The Effect of ABCG2 Genotype on the Population Pharmacokinetics of Sunitinib in Patients With Renal Cell Carcinoma
Background: Sunitinib, a multitargeted tyrosine kinase inhibitor, offers favorable therapeutic outcomes to patients with advanced… 
2014
2014
Sunitinib-induced severe toxicities in a Japanese patient with the ABCG2 421 AA genotype
BackgroundSunitinib is a multi-targeted receptor tyrosine kinase inhibitor that acts against receptors for vascular endothelial… 
Highly Cited
2010
Highly Cited
2010
Additive effects of drug transporter genetic polymorphisms on irinotecan pharmacokinetics/pharmacodynamics in Japanese cancer patients
PurposeEffects of genetic polymorphisms/variations of ABCB1, ABCC2, ABCG2 and SLCO1B1 in addition to “UGT1A1*28 or *6” on… 
Highly Cited
2008
Highly Cited
2008
Synergistic interaction of ABCB1 and ABCG2 polymorphisms predicts the prevalence of toxic encephalopathy during anticancer chemotherapy
Polymorphisms of the ABCB1 (MDR1) and ABCG2 (BCRP) genes were reported to alter the expression and function of these drug… 
Highly Cited
2006
Highly Cited
2006
DGAT1 and ABCG2 polymorphism in Indian cattle (Bos indicus) and buffalo (Bubalus bubalis) breeds
BackgroundIndian cattle (Bos indicus) and riverine buffalo (Bubalus bubalis) give a poor yield of milk but it has a high fat and… 
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