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ATN-658

National Institutes of Health

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Monoclonal Antibodies

Papers overview

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2017
2017
Preclinical uPAR-targeted multimodal imaging of locoregional head-and-neck cancers
Objectives: Establishing adequate resection margins and lymphatic mapping are crucial for the prognosis of oral cancer patients… 
2015
2015
Abstract POSTER-THER-1440: Targeted delivery of doxorubicin loaded nanobins to ovarian cancer cells through the urokinase plasminogen activator system
The therapeutic efficacy of antitumor drugs is often limited by non-specific, systematic delivery. Here we report a novel… 
2014
2014
Correction: Identification of a New Epitope in uPAR as a Target for the Cancer Therapeutic Monoclonal Antibody ATN-658, a Structural Homolog of the uPAR Binding Integrin CD11b (αM)
The second author’s name is incorrect. The correct name is ‘‘Cai Yuan.’’ The correct citation is: Xu X, Yuan C, Wei Y, Donate F… 
2014
2014
Correction: Identification of a New Epitope in uPAR as a Target for the Cancer Therapeutic Monoclonal Antibody ATN-658, a Structural Homolog of the uPAR Binding Integrin CD11b (αM)
2013
2013
Abstract 863: Inhibition of breast cancer metastaticprogression by a novel uPAR targeted monoclonal antibody, ATN-658, correlateswith the uPAR expression.
The urokinase plasminogen activator receptor (uPAR) has been implicated in the progression of metastatic disease in a number of… 
2007
2007
A selective anti-urokinase receptor (uPAR) antibody (ATN-658) blocks prostate cancer growth, migration, invasion and skeletal metastasis in vitro and in vivo
4094 Over expression of urokinase plasminogen activator (uPA) and its receptor (uPAR) have been strongly correlated with poor… 
2005
2005
In vitro and in vivo characterization of a monoclonal antibody, ATN-658, targeting the uPA system
6179 A substantial body of in vitro and in vivo data has implicated the urokinase plasminogen activator system, comprised of the… 
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