ATG16L1 gene

Known as: WDR30, Autophagy Related 16-Like 1 (S. cerevisiae) Gene, APG16-LIKE 
This gene plays a role in the regulation of autophagy.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
A coding polymorphism (Thr300Ala) in the essential autophagy gene, autophagy related 16-like 1 (ATG16L1), confers increased risk… (More)
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Highly Cited
2010
Highly Cited
2010
It is unclear why disease occurs in only a small proportion of persons carrying common risk alleles of disease susceptibility… (More)
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Highly Cited
2010
Highly Cited
2010
Autophagy is emerging as a crucial defense mechanism against bacteria, but the host intracellular sensors responsible for… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND & AIMS The identification of numerous genes that confer susceptibility to Crohn's disease (CD) indicates that this… (More)
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Highly Cited
2008
Highly Cited
2008
Susceptibility to Crohn’s disease, a complex inflammatory disease involving the small intestine, is controlled by over 30 loci… (More)
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Highly Cited
2008
Highly Cited
2008
Systems for protein degradation are essential for tight control of the inflammatory immune response. Autophagy, a bulk… (More)
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Highly Cited
2008
Highly Cited
2008
The genetic risk factors predisposing individuals to the development of inflammatory bowel disease are beginning to be deciphered… (More)
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Highly Cited
2007
Highly Cited
2007
We performed a genome-wide association study of 19,779 nonsynonymous SNPs in 735 individuals with Crohn disease and 368 controls… (More)
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Highly Cited
2007
Highly Cited
2007
A genome-wide association scan in individuals with Crohn's disease by the Wellcome Trust Case Control Consortium detected strong… (More)
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Highly Cited
2007
Highly Cited
2007
We present a genome-wide association study of ileal Crohn disease and two independent replication studies that identify several… (More)
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