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AT 1015

Known as: AT-1015 
National Institutes of Health

Papers overview

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Review
2004
Review
2004
Randomized trial of AT-1015 for treatment of intermittent claudication. A novel 5-hydroxytryptamine antagonist with no evidence of efficacy
AT-1015 is a novel selective 5-HT2A serotonin receptor antagonist that is known to impair platelet aggregation and… 
2004
2004
Safety of AT-1015, a novel 5-HT2A antagonist, in combination with high-dose aspirin: an open-label study.
OBJECTIVE To assess the safety of AT-1015 in combination with high-dose aspirin (300 mg daily). Study subjects were 17 healthy… 
2003
2003
Insurmountable antagonism of AT‐1015, a 5‐HT2 antagonist, on serotonin‐induced endothelium‐dependent relaxation in porcine coronary artery
The purpose of this study was to examine the inhibitory effects of AT‐1015, a newly synthesized 5‐HT2 receptor antagonist, on… 
2002
2002
AT‐1015, a newly synthesized 5‐HT2 receptor antagonist, dissociates slowly from the 5‐HT2 receptor sites in rabbit cerebral cortex membrane
The purpose of this study was to investigate the association and dissociation kinetics of [3H]AT‐1015 from 5‐HT2 receptors in… 
2001
2001
Assessment of affinity and dissociation ability of a newly synthesized 5-HT2 antagonist, AT-1015: comparison with other 5-HT2 antagonists.
This study investigated the binding affinities of a newly synthesized 5-HT2 antagonist, AT-1015 (N-[2-[4-(5H-dibenzo[a,d… 
2001
2001
Binding affinity of a newly synthesized 5-HT2 antagonist, AT-1015 (N-[2-[4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-piperidino]ethyl]-1-formyl-4-piperidinecarboxamide monohydrochloride monohydrate), in…
The object of this study was to investigate the binding affinity of a newly synthesized 5-HT2 antagonist, (N-[2-[4-(5H-dibenzo[a… 
2000
2000
Inhibitory effects of a newly synthesized 5-HT2 receptor antagonist, AT-1015 (N-[2-[4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)piperidino]-ethyl]-1-for myl-4-piperidinecarboxamide monohydrochloride…
Inhibitory effects of a newly synthesized 5-HT2 receptor antagonist, AT-1015 (N-[2-[4-(5H-dibenzo[a,d]cyclohepten-5-ylidene… 
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