ASNS gene

Known as: ASNS, asparagine synthetase (glutamine-hydrolyzing), HUMAN COMPLEMENT FOR HAMSTER TEMPERATURE-SENSITIVE MUTANT ts11 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2018
051019942018

Papers overview

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2014
2014
L-Asparaginase (L-ASP) is a key component of therapy for acute lymphoblastic leukemia. Its mechanism of action, however, is still… (More)
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Highly Cited
2010
Highly Cited
2010
The transcription factor ATF4 regulates the expression of genes involved in amino acid metabolism, redox homeostasis and ER… (More)
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2008
2008
BACKGROUND Asparaginase (ASNase) is an essential component of most treatment protocols for childhood acute lymphoblastic leukemia… (More)
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Highly Cited
2007
Highly Cited
2007
The integrated stress response (ISR) is defined as a highly conserved response to several stresses that converge to the induction… (More)
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Highly Cited
2007
Highly Cited
2007
Because of their low asparagine synthetase (ASNS) expression and asparagine biosynthesis, acute lymphoblastic leukemia (ALL… (More)
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2007
2007
Mitochondrial dysfunction caused by mutations in mitochondrial DNA (mtDNA) is related to a variety of diseases including MELAS… (More)
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2005
2005
To investigate the effect of l-asparaginase on acute lymphoblastic leukemia (ALL), we used cDNA microarrays to obtain a genome… (More)
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Highly Cited
2004
Highly Cited
2004
Expression of human asparagine synthetase (ASNS), which catalyzes asparagine and glutamate biosynthesis, is transcriptionally… (More)
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2003
2003
Transcription from the ASNS (asparagine synthetase) gene is increased in response to either amino acid (amino acid response) or… (More)
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2003
2003
This paper is one in a series from the American Society of Nutritional Sciences Long Range Planning Committee, in which we are… (More)
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