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ASNS gene

Known as: ASNS, asparagine synthetase (glutamine-hydrolyzing), HUMAN COMPLEMENT FOR HAMSTER TEMPERATURE-SENSITIVE MUTANT ts11 
 
National Institutes of Health

Related topics

Related topics

3 relations
AsparagineAspartate-Ammonia Ligaseasparagine synthase (glutamine-hydrolyzing) activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Diaphragmatic Eventration in Sisters with Asparagine Synthetase Deficiency: A Novel Homozygous ASNS Mutation and Expanded Phenotype.
BACKGROUND Asparagine Synthetase Deficiency (ASNSD; OMIM #615574) is a newly described rare autosomal recessive neurometabolic… Expand
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2016
2016
Hyperekplexia, microcephaly and simplified gyral pattern caused by novel ASNS mutations, case report
BackgroundAsparagine synthetase deficiency (OMIM# 615574) is a very rare newly described neurometabolic disorder characterized by… Expand
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2015
2015
Silver nanoparticles activate endoplasmic reticulum stress signaling pathway in cell and mouse models: The role in toxicity evaluation.
Silver nanoparticles (AgNPs) attract considerable public attention both for their antimicrobial properties and their potential… Expand
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2011
2011
Gestational low protein diet selectively induces the amino acid response pathway target genes in the liver of offspring rats through transcription factor binding and histone modifications.
The amino acid response (AAR) pathway detects a deficiency of dietary amino acid or protein. To investigate the impact of… Expand
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2009
2009
Transcriptional induction of the human asparagine synthetase gene during the unfolded protein response does not require the ATF6 and IRE1/XBP1 arms of the pathway.
The UPR (unfolded protein response) pathway comprises three signalling cascades mediated by the ER (endoplasmic reticulum) stress… Expand
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2007
2007
CHOP (C/EBP homologous protein) and ASNS (asparagine synthetase) induction in cybrid cells harboring MELAS and NARP mitochondrial DNA mutations.
Mitochondrial dysfunction caused by mutations in mitochondrial DNA (mtDNA) is related to a variety of diseases including MELAS… Expand
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2005
2005
Regulation of asparagine synthetase gene transcription by the basic region leucine zipper transcription factors ATF5 and CHOP
Abstract Asparagine synthetase catalyses the glutamine- and ATP-dependent conversion of aspartic acid to asparagine. In human… Expand
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Highly Cited
2003
Highly Cited
2003
Amino acid deprivation and endoplasmic reticulum stress induce expression of multiple activating transcription factor-3 mRNA species that, when overexpressed in HepG2 cells, modulate transcription by…
Transcription from the ASNS (asparagine synthetase) gene is increased in response to either amino acid (amino acid response) or… Expand
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2002
2002
The mechanism for transcriptional activation of the human ATA2 transporter gene by amino acid deprivation is different than that for asparagine synthetase.
After amino acid deprivation, the mRNA content for both asparagine synthetase (AS) and the system A transporter ATA2 is increased… Expand
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1991
1991
Regulation of asparagine synthetase gene expression by amino acid starvation.
We have studied the regulation of expression of the asparagine synthetase (AS) gene in ts11 cells, a mutant of BHK hamster cells… Expand
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