Aspartate-Ammonia Ligase

Known as: Aspartate-Ammonia Ligase [Chemical/Ingredient], Synthetase, Asparagine, L-Aspartate:ammonia ligase (AMP-forming) 
An enzyme that catalyzes the formation of asparagine from ammonia and aspartic acid, in the presence of ATP. EC 6.3.1.1.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Many cancer cells consume large quantities of glutamine to maintain TCA cycle anaplerosis and support cell survival. It was… (More)
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Highly Cited
2010
Highly Cited
2010
The transcription factor ATF4 regulates the expression of genes involved in amino acid metabolism, redox homeostasis and ER… (More)
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Highly Cited
2007
Highly Cited
2007
Because of their low asparagine synthetase (ASNS) expression and asparagine biosynthesis, acute lymphoblastic leukemia (ALL… (More)
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Highly Cited
2006
Highly Cited
2006
Chromosome rearrangement, a hallmark of cancer, has profound effects on carcinogenesis and tumor phenotype. We used a panel of 60… (More)
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Highly Cited
2004
Highly Cited
2004
Expression of human asparagine synthetase (ASNS), which catalyzes asparagine and glutamate biosynthesis, is transcriptionally… (More)
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Review
2001
Review
2001
The three-dimensional structures of tryptophan synthase, carbamoyl phosphate synthetase, glutamine phosphoribosylpyrophosphate… (More)
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Highly Cited
2001
Highly Cited
2001
A subtractive tomato (Lycopersicon esculentum) root cDNA library enriched in genes up-regulated by changes in plant mineral… (More)
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Highly Cited
2000
Highly Cited
2000
Microarray and RNA gel blot analyses were performed to identify Arabidopsis genes that responded to nitrate at both low (250… (More)
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Highly Cited
1998
Highly Cited
1998
In plants, the amino acid asparagine serves as an important nitrogen transport compound whose levels are dramatically regulated… (More)
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Highly Cited
1994
Highly Cited
1994
Here, we characterize a cDNA encoding a glutamine-dependent asparagine synthetase (ASN1) from Arabidopsis thaliana and assess the… (More)
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