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Differentiation of mouse myeloid leukemia cells induced by 1 alpha,25-dihydroxyvitamin D3.
- E. Abe, C. Miyaura, T. Suda
- Biology, ChemistryProceedings of the National Academy of Sciences…
- 1 August 1981
The results suggest the possibility that, in addition to its wellknown biological activities in enhancing intestinal calcium transport and bone mineral mobilization, 1 alpha, 25-dihydroxyvitamin D3 is involved in the differentiation of bone marrow cells.
SP-40,40 is a constituent of Alzheimer's amyloid
β-amyloid contained SP-40,40 in a form different from that in the soluble membrane attack complex (SMAC, SC5b-9) of the complement, which contains S-protein as well as SP- 40,40.
Molecular cloning and characterization of a novel developmentally regulated gene, Bdm1, showing predominant expression in postnatal rat brain.
Anti-HIV (human immunodeficiency virus) activity of sulfated paramylon.
Inhibition of neurite outgrowth by reduced level of NDRG4 protein in antisense transfected PC12 cells.
Benzylideneascorbate induces apoptosis in L929 tumor cells.
Results indicate a possible mechanism by which SBA induces tumor regression in vivo and show cell shrinkage, disappearance of cell surface microvilli, chromatin condensation and DNA fragmentation into nucleosomal oligomers characteristic of apoptosis.
Relationship between ascorbyl radical intensity and apoptosis-inducing activity.
Data suggest the possible involvement of the ascorbyl radical in apoptosis induction by ascorbic acid-related compounds in human promyelocytic leukemic HL-60 cells.
O2- scavenging activity of lignins, tannins and PSK.
The results suggest that O2- might be scavenged both directly by iodination stimulators, and by other oxygen radicals produced by activation of myeloperoxidase-mediated reaction.
Mitogenic activity of natural and synthetic lignins against cultured splenocytes.
Various natural lignified materials and synthetic dehydrogenation polymers prepared from several phenylpropenoids were investigated for their mitogenic activity, but their stimulating activity was significantly decreased when the splenocytes were pretreated with anti-Thy-1.2 monoclonal antibody and rabbit complement.
Effect of glutathione-modulating compounds on hydrogen-peroxide-induced cytotoxicity in human glioblastoma and glioma cell lines
- M. Iida, S. Sunaga, Kiyoshi Matsumoto
- Biology, ChemistryJournal of Cancer Research and Clinical Oncology
The results suggest that drug sensitivity of tumor cells can be modified by glutathione-modulating compounds.