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AS 252424

Known as: AS-252424, AS252424 
 

Topic mentions per year

Topic mentions per year

2005-2017
012320052017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Phosphoinositide 3-Kinase Gamma Contributes to Neuroinflammation in a Rat Model of Surgical Brain Injury.
Neuroinflammation plays an important role in the pathophysiology of surgical brain injury (SBI). Phosphoinositide 3-kinase gamma… (More)
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2014
2014
Mechanisms involved in kinin-induced glioma cells proliferation: the role of ERK1/2 and PI3K/Akt pathways
Gliomas are the most common malignant brain tumors in adults. Bradykinin (BK) displays an important role in cancer, although the… (More)
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2013
2013
Effects of isoform-selective phosphatidylinositol 3-kinase inhibitors on osteoclasts: actions on cytoskeletal organization, survival, and resorption.
Phosphatidylinositol 3-kinases (PI3K) participate in numerous signaling pathways, and control distinct biological functions… (More)
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2013
2013
Phosphatidylinositol 3-kinase-γ signaling promotes Campylobacter jejuni-induced colitis through neutrophil recruitment in mice.
Crypt abscesses caused by excessive neutrophil accumulation are prominent features of human campylobacteriosis and its associated… (More)
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2013
2013
Phosphoinositide 3-Kinase Dependent Inhibition as a Broad Basis for Opponent Coding in Mammalian Olfactory Receptor Neurons
Phosphoinositide 3-kinase (PI3K) signaling has been implicated in mediating inhibitory odorant input to mammalian olfactory… (More)
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2012
2012
Pharmacological profile of phosphatidylinositol 3-kinases and related phosphatidylinositols mediating endothelin(A) receptor-operated native TRPC channels in rabbit coronary artery myocytes.
BACKGROUND AND PURPOSE Endothelin(A) (ET(A) ) receptor-operated canonical transient receptor potential (TRPC) channels mediate Ca… (More)
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2011
2011
Phosphoinositide 3-kinase-dependent antagonism in mammalian olfactory receptor neurons.
Phosphoinositide signaling, in particular, phosphoinositide 3-kinase (PI3K) signaling, has been implicated in mediating… (More)
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2010
2010
Role of phosphoinositide 3-kinase beta in platelet aggregation and thromboxane A2 generation mediated by Gi signalling pathways.
PI3Ks (phosphoinositide 3-kinases) play a critical role in platelet functional responses. PI3Ks are activated upon P2Y12 receptor… (More)
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2009
2009
Role of phosphoinositide 3-kinase beta in glycoprotein VI-mediated Akt activation in platelets.
Glycoprotein (GP) VI is a critical platelet collagen receptor. Phosphoinositide 3-kinase (PI3K) plays an important role in GPVI… (More)
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Highly Cited
2006
Highly Cited
2006
Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma.
Class I phosphoinositide 3-kinases (PI3Ks), in particular PI3Kgamma, have become attractive drug targets for inflammatory and… (More)
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