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AS 252424

Known as: AS-252424, AS252424 
National Institutes of Health

Papers overview

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Review
2015
Review
2015
PI3K inhibitors in inflammation, autoimmunity and cancer
2015
2015
Phosphoinositide 3-Kinase Gamma Contributes to Neuroinflammation in a Rat Model of Surgical Brain Injury
Neuroinflammation plays an important role in the pathophysiology of surgical brain injury (SBI). Phosphoinositide 3-kinase gamma… 
2015
2015
Function of the Chondrocyte PI-3 Kinase-Akt Signaling Pathway is Stimulus Dependent
2014
2014
Mechanisms involved in kinin-induced glioma cells proliferation: the role of ERK1/2 and PI3K/Akt pathways
Gliomas are the most common malignant brain tumors in adults. Bradykinin (BK) displays an important role in cancer, although the… 
2013
2013
Effects of Isoform-selective Phosphatidylinositol 3-Kinase Inhibitors on Osteoclasts
Background: Little is known about the function of specific phosphatidylinositol 3-kinase (PI3K) isoforms in osteoclasts. Results… 
2011
2011
Phosphoinositide 3-Kinase-Dependent Antagonism in Mammalian Olfactory Receptor Neurons
Phosphoinositide signaling, in particular, phosphoinositide 3-kinase (PI3K) signaling, has been implicated in mediating… 
Highly Cited
2010
Highly Cited
2010
Role of phosphoinositide 3-kinase beta in platelet aggregation and thromboxane A2 generation mediated by Gi signalling pathways.
PI3Ks (phosphoinositide 3-kinases) play a critical role in platelet functional responses. PI3Ks are activated upon P2Y12 receptor… 
2010
2010
Involvement of phosphoinositide 3-kinase γ in the neuro-inflammatory response and cognitive impairments induced by β-amyloid 1–40 peptide in mice
Highly Cited
2009
Highly Cited
2009
Role of Phosphoinositide 3-Kinase β in Glycoprotein VI-mediated Akt Activation in Platelets*
Glycoprotein (GP) VI is a critical platelet collagen receptor. Phosphoinositide 3-kinase (PI3K) plays an important role in GPVI… 
Highly Cited
2006
Highly Cited
2006
Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma.
Class I phosphoinositide 3-kinases (PI3Ks), in particular PI3Kgamma, have become attractive drug targets for inflammatory and… 
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