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AS 1402
Known as:
AS-1402
, AS1402
, R1550
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Monoclonal Antibodies
monoclonal antibody HuHMFG1
Papers overview
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Highly Cited
2011
Highly Cited
2011
Randomized Phase II Trial of Letrozole plus Anti-MUC1 Antibody AS1402 in Hormone Receptor–Positive Locally Advanced or Metastatic Breast Cancer
N. Ibrahim
,
K. Yariz
,
+12 authors
M. Pegram
Clinical Cancer Research
2011
Corpus ID: 44846558
Purpose: AS1402 is a humanized immunoglobulin G1 antibody that targets the aberrantly glycosylated antigen MUC1, which is…
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2010
2010
Population pharmacokinetics of the humanised monoclonal antibody, HuHMFG1 (AS1402), derived from a phase I study on breast cancer
B. Royer
,
W. Yin
,
+5 authors
X. Pivot
British Journal of Cancer
2010
Corpus ID: 18385429
Background:HuHMFG1 (AS1402) is a humanised monoclonal antibody that has undergone a phase I trial in metastatic breast cancer…
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2009
2009
Phase I dose escalation pharmacokinetic assessment of intravenous humanized anti-MUC1 antibody AS1402 in patients with advanced breast cancer
M. Pegram
,
V. Borges
,
+6 authors
Nigel Courtenay Luck
Breast Cancer Research
2009
Corpus ID: 3755518
IntroductionMUC1 is a cell-surface glycoprotein that establishes a molecular barrier at the epithelial surface and engages in…
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2008
2008
Toll-like receptor agonists and invariant natural killer T-cells enhance antibody-dependent cell-mediated cytotoxicity (ADCC).
M. Moreno
,
B. Mol
,
+5 authors
H. Bontkes
Cancer Letters
2008
Corpus ID: 46121533
2006
2006
Phase I pharmacokinetics (PK) of humanized anti-MUC-1 antibody R1550.
M. Pegram
,
V. Borges
,
+7 authors
N. Courtenay-Luck
Journal of Clinical Oncology
2006
Corpus ID: 40268925
2533 Background: MUC-1 glycoprotein establishes a molecular barrier at the epithelial surface, and engages in morphogenetic…
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