monoclonal antibody HuHMFG1

Known as: MOAB HuHMFG1, HuHMFG1, humanized human milk fat globule-1 monoclonal antibody 
A monoclonal antibody that binds to the protein MUC1, which is found on breast, ovarian, pancreatic, gastric, and colon cancer cells. Monoclonal… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2017
0119932017

Papers overview

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2017
2017
BACKGROUND Mucin glycoprotein 1 (MUC1) is a glycosylated transmembrane protein on epithelial cells. We investigate MUC1 as a… (More)
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2014
2014
Antibody-dependent, cell-mediated cytotoxicity (ADCC) is one of the major mechanisms underlying the clinical efficacy of… (More)
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2010
2010
Background:HuHMFG1 (AS1402) is a humanised monoclonal antibody that has undergone a phase I trial in metastatic breast cancer… (More)
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2004
2004
Anti-MUC1 single-chain Fv (scFv) fragments generated from the humanised antibody huHMFG1 had adequate antigen-binding properties… (More)
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1994
1994
A recombinant Fv (variable fragment) has been produced for the murine monoclonal antibody HMFG1. This antibody was raised against… (More)
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1993
1993
A human antibody with milk mucin specificity was obtained by transferring the complementarity determining regions (CDR) of the… (More)
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