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ARI-4175

National Institutes of Health

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2 relations

Broader (2)

Boron CompoundsDipeptides

Papers overview

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2014
2014
A pan inhibitor of DASH family enzymes induces immunogenic modulation and sensitizes murine and human carcinoma cells to antigen-specific cytotoxic T lymphocyte killing: implications for combination…
2014
2014
Abstract 2537: Antibody dependent cytotoxicity is enhanced by Ari-4175 through NK cell activation
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA We previously reported that the prolyl peptidase inhibitor… 
2013
2013
A Pan-Inhibitor of DASH Family Enzymes Induces Immune-mediated Regression of Murine Sarcoma and Is a Potent Adjuvant to Dendritic Cell Vaccination and Adoptive T-cell Therapy
Multimodality therapy consisting of surgery, chemotherapy, and radiation will fail in approximately 40% of patients with… 
2013
2013
Abstract 494: Immunomodulatory effects of a small molecule dipeptidyl peptidase inhibitor, Ari-4175, are mediated through NK cell activation in a colorectal cancer model.
Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC Introduction: A possible mechanism of the antitumor… 
2012
2012
Abstract 5226: Potential anti-tumor effect of a small molecule dipeptidyl peptidase inhibitor, 4175, in colorectal cancer
Introduction: Cetuximab is an effective therapeutic agent in a number of malignancies. Current data indicates that about 30% of… 
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