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ARHGEF25 gene

Known as: RAC- AND CDC42-SPECIFIC GUANINE NUCLEOTIDE EXCHANGE FACTOR, Rho guanine nucleotide exchange factor 25, p63RhoGEF 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Enantioselective toxic effects and biodegradation of benalaxyl in Scenedesmus obliquus.
Enantioselectivity in ecotoxicity and biodegradation of chiral pesticide benalaxyl to freshwater algae Scenedesmus obliquus was… 
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Highly Cited
2011
Highly Cited
2011
p63RhoGEF Couples G&agr;q/11-Mediated Signaling to Ca2+ Sensitization of Vascular Smooth Muscle Contractility
Rationale: In normal and diseased vascular smooth muscle (SM), the RhoA pathway, which is activated by multiple agonists through… 
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Highly Cited
2010
Highly Cited
2010
p63RhoGEF--a key mediator of angiotensin II-dependent signaling and processes in vascular smooth muscle cells.
The purpose of our study was to investigate the role of endogenous p63RhoGEF in G(q/11)-dependent RhoA activation and signaling… 
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2008
2008
IT'S IN THE GENES: EXPLORING RELATIONSHIPS BETWEEN CRITICAL THINKING AND PROBLEM SOLVING IN UNDERGRADUATE AGRISCIENCE STUDENTS' SOLUTIONS TO PROBLEMS IN MENDELIAN GENETICS
This study was conducted to examine the statistical relationship between problem solving and critical thinking to guide future… 
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Highly Cited
2007
Highly Cited
2007
Structure of Gαq-p63RhoGEF-RhoA Complex Reveals a Pathway for the Activation of RhoA by GPCRs
The guanine nucleotide exchange factor p63RhoGEF is an effector of the heterotrimeric guanine nucleotide–binding protein (G… 
Highly Cited
2005
Highly Cited
2005
The Guanine Nucleotide Exchange Factor p63RhoGEF, a Specific Link between Gq/11-coupled Receptor Signaling and RhoA*
The monomeric GTPase RhoA, which is a key regulator of numerous cellular processes, is activated by a variety of G protein… 
Highly Cited
2004
Highly Cited
2004
GEFT, A Rho Family Guanine Nucleotide Exchange Factor, Regulates Neurite Outgrowth and Dendritic Spine Formation*
The Rho family of small GTPases controls a wide range of cellular processes in eukaryotic cells, such as normal cell growth… 
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2004
2004
p63RhoGEF and GEFT are Rho-specific guanine nucleotide exchange factors encoded by the same gene
Activation of Rho GTPases, which play pivotal roles in diverse cellular functions, is catalysed by specific guanine nucleotide… 
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Highly Cited
2003
Highly Cited
2003
A Rac/Cdc42-specific Exchange Factor, GEFT, Induces Cell Proliferation, Transformation, and Migration*
The Rho family of small GTPases, including Rho, Rac, and Cdc42, play essential roles in diverse cellular functions. The ability… 
Highly Cited
2002
Highly Cited
2002
Human p63RhoGEF, a novel RhoA-specific guanine nucleotide exchange factor, is localized in cardiac sarcomere.
The Rho small GTPases are crucial proteins involved in regulation of signal transduction cascades from extracellular stimuli to… 
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