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ARHGEF25 gene

Known as: RAC- AND CDC42-SPECIFIC GUANINE NUCLEOTIDE EXCHANGE FACTOR, Rho guanine nucleotide exchange factor 25, p63RhoGEF 
 
National Institutes of Health

Papers overview

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2012
2012
Enantioselective toxic effects and biodegradation of benalaxyl in Scenedesmus obliquus.
Enantioselectivity in ecotoxicity and biodegradation of chiral pesticide benalaxyl to freshwater algae Scenedesmus obliquus was… Expand
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2011
2011
p63RhoGEF couples Gα(q/11)-mediated signaling to Ca2+ sensitization of vascular smooth muscle contractility.
RATIONALE In normal and diseased vascular smooth muscle (SM), the RhoA pathway, which is activated by multiple agonists through G… Expand
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2010
2010
p63RhoGEF--a key mediator of angiotensin II-dependent signaling and processes in vascular smooth muscle cells.
The purpose of our study was to investigate the role of endogenous p63RhoGEF in G(q/11)-dependent RhoA activation and signaling… Expand
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2010
2010
Galpha q allosterically activates and relieves autoinhibition of p63RhoGEF.
Galpha(q) directly activates p63RhoGEF and closely related catalytic domains found in Trio and Kalirin, thereby linking G(q… Expand
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2008
2008
It's in the Genes: Exploring Relationships between Critical Thinking and Problem Solving in Undergraduate Agriscience Students' Solutions to Problems in Mendelian Genetics.
This study was conducted to examine the statistical relationship between problem solving and critical thinking to guide future… Expand
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2008
2008
Assembly of high order G alpha q-effector complexes with RGS proteins.
Transmembrane signaling through G alpha(q)-coupled receptors is linked to physiological processes such as cardiovascular… Expand
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2006
2006
The Rho-family guanine nucleotide exchange factor GEFT enhances retinoic acid- and cAMP-induced neurite outgrowth.
The Rho GTPases are important regulators of neurite outgrowth and pathfinding. We have recently reported that a Rho-family… Expand
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2005
2005
Modulation of muscle regeneration, myogenesis, and adipogenesis by the Rho family guanine nucleotide exchange factor GEFT.
Rho family guanine nucleotide exchange factors (GEFs) regulate diverse cellular processes including cytoskeletal reorganization… Expand
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Highly Cited
2004
Highly Cited
2004
GEFT, a Rho family guanine nucleotide exchange factor, regulates neurite outgrowth and dendritic spine formation.
The Rho family of small GTPases controls a wide range of cellular processes in eukaryotic cells, such as normal cell growth… Expand
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2002
2002
Human p63RhoGEF, a novel RhoA-specific guanine nucleotide exchange factor, is localized in cardiac sarcomere.
The Rho small GTPases are crucial proteins involved in regulation of signal transduction cascades from extracellular stimuli to… Expand
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