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ARHGEF25 gene
Known as:
RAC- AND CDC42-SPECIFIC GUANINE NUCLEOTIDE EXCHANGE FACTOR
, Rho guanine nucleotide exchange factor 25
, p63RhoGEF
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Enantioselective toxic effects and biodegradation of benalaxyl in Scenedesmus obliquus.
Ledan Huang
,
Dahai Lu
,
Jinling Diao
,
Z. Zhou
Chemosphere
2012
Corpus ID: 206645686
Enantioselectivity in ecotoxicity and biodegradation of chiral pesticide benalaxyl to freshwater algae Scenedesmus obliquus was…
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Highly Cited
2011
Highly Cited
2011
p63RhoGEF Couples G&agr;q/11-Mediated Signaling to Ca2+ Sensitization of Vascular Smooth Muscle Contractility
Ko Momotani
,
M. Artamonov
,
D. Utepbergenov
,
U. Derewenda
,
Z. Derewenda
,
A. Somlyo
Circulation research
2011
Corpus ID: 17210689
Rationale: In normal and diseased vascular smooth muscle (SM), the RhoA pathway, which is activated by multiple agonists through…
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Highly Cited
2010
Highly Cited
2010
p63RhoGEF--a key mediator of angiotensin II-dependent signaling and processes in vascular smooth muscle cells.
Christina M. Wuertz
,
A. Lorincz
,
C. Vettel
,
M. A. Thomas
,
T. Wieland
,
S. Lutz
FASEB journal : official publication of the…
2010
Corpus ID: 25651556
The purpose of our study was to investigate the role of endogenous p63RhoGEF in G(q/11)-dependent RhoA activation and signaling…
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2010
2010
Galpha q allosterically activates and relieves autoinhibition of p63RhoGEF.
A. Shankaranarayanan
,
Cassandra A Boguth
,
+5 authors
John J. G. Tesmer
Cellular signalling
2010
Corpus ID: 8223867
Galpha(q) directly activates p63RhoGEF and closely related catalytic domains found in Trio and Kalirin, thereby linking G(q…
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Highly Cited
2007
Highly Cited
2007
Structure of Gαq-p63RhoGEF-RhoA Complex Reveals a Pathway for the Activation of RhoA by GPCRs
S. Lutz
,
A. Shankaranarayanan
,
+8 authors
John J. G. Tesmer
Science
2007
Corpus ID: 2418867
The guanine nucleotide exchange factor p63RhoGEF is an effector of the heterotrimeric guanine nucleotide–binding protein (G…
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Highly Cited
2005
Highly Cited
2005
The Guanine Nucleotide Exchange Factor p63RhoGEF, a Specific Link between Gq/11-coupled Receptor Signaling and RhoA*
S. Lutz
,
Andrea Freichel-Blomquist
,
+4 authors
T. Wieland
Journal of Biological Chemistry
2005
Corpus ID: 11394006
The monomeric GTPase RhoA, which is a key regulator of numerous cellular processes, is activated by a variety of G protein…
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Highly Cited
2004
Highly Cited
2004
GEFT, A Rho Family Guanine Nucleotide Exchange Factor, Regulates Neurite Outgrowth and Dendritic Spine Formation*
B. Bryan
,
V. Kumar
,
L. Stafford
,
Y. Cai
,
Gangyi Wu
,
M. Liu
Journal of Biological Chemistry
2004
Corpus ID: 3215802
The Rho family of small GTPases controls a wide range of cellular processes in eukaryotic cells, such as normal cell growth…
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2004
2004
p63RhoGEF and GEFT are Rho-specific guanine nucleotide exchange factors encoded by the same gene
S. Lutz
,
Andrea Freichel-Blomquist
,
U. Rümenapp
,
M. Schmidt
,
K. Jakobs
,
T. Wieland
Naunyn-Schmiedeberg's Archives of Pharmacology
2004
Corpus ID: 19812449
Activation of Rho GTPases, which play pivotal roles in diverse cellular functions, is catalysed by specific guanine nucleotide…
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Highly Cited
2003
Highly Cited
2003
A Rac/Cdc42-specific Exchange Factor, GEFT, Induces Cell Proliferation, Transformation, and Migration*
Xiangrong Guo
,
L. Stafford
,
+6 authors
M. Liu
The Journal of Biological Chemistry
2003
Corpus ID: 8976652
The Rho family of small GTPases, including Rho, Rac, and Cdc42, play essential roles in diverse cellular functions. The ability…
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Highly Cited
2002
Highly Cited
2002
Human p63RhoGEF, a novel RhoA-specific guanine nucleotide exchange factor, is localized in cardiac sarcomere.
M. Souchet
,
Elodie Portales-Casamar
,
+9 authors
T. Calmels
Journal of cell science
2002
Corpus ID: 36752245
The Rho small GTPases are crucial proteins involved in regulation of signal transduction cascades from extracellular stimuli to…
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