Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

ARHGEF25 gene

Known as: RAC- AND CDC42-SPECIFIC GUANINE NUCLEOTIDE EXCHANGE FACTOR, Rho guanine nucleotide exchange factor 25, p63RhoGEF 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Enantioselective toxic effects and biodegradation of benalaxyl in Scenedesmus obliquus.
Enantioselectivity in ecotoxicity and biodegradation of chiral pesticide benalaxyl to freshwater algae Scenedesmus obliquus was… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • table 2
Highly Cited
2011
Highly Cited
2011
p63RhoGEF Couples G&agr;q/11-Mediated Signaling to Ca2+ Sensitization of Vascular Smooth Muscle Contractility
Rationale: In normal and diseased vascular smooth muscle (SM), the RhoA pathway, which is activated by multiple agonists through… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
2010
Highly Cited
2010
p63RhoGEF--a key mediator of angiotensin II-dependent signaling and processes in vascular smooth muscle cells.
The purpose of our study was to investigate the role of endogenous p63RhoGEF in G(q/11)-dependent RhoA activation and signaling… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
2010
2010
Galpha q allosterically activates and relieves autoinhibition of p63RhoGEF.
Galpha(q) directly activates p63RhoGEF and closely related catalytic domains found in Trio and Kalirin, thereby linking G(q… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Highly Cited
2007
Highly Cited
2007
Structure of Gαq-p63RhoGEF-RhoA Complex Reveals a Pathway for the Activation of RhoA by GPCRs
The guanine nucleotide exchange factor p63RhoGEF is an effector of the heterotrimeric guanine nucleotide–binding protein (G… Expand
Highly Cited
2005
Highly Cited
2005
The Guanine Nucleotide Exchange Factor p63RhoGEF, a Specific Link between Gq/11-coupled Receptor Signaling and RhoA*
The monomeric GTPase RhoA, which is a key regulator of numerous cellular processes, is activated by a variety of G protein… Expand
Highly Cited
2004
Highly Cited
2004
GEFT, A Rho Family Guanine Nucleotide Exchange Factor, Regulates Neurite Outgrowth and Dendritic Spine Formation*
The Rho family of small GTPases controls a wide range of cellular processes in eukaryotic cells, such as normal cell growth… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
2004
2004
p63RhoGEF and GEFT are Rho-specific guanine nucleotide exchange factors encoded by the same gene
Activation of Rho GTPases, which play pivotal roles in diverse cellular functions, is catalysed by specific guanine nucleotide… Expand
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Highly Cited
2003
Highly Cited
2003
A Rac/Cdc42-specific Exchange Factor, GEFT, Induces Cell Proliferation, Transformation, and Migration*
The Rho family of small GTPases, including Rho, Rac, and Cdc42, play essential roles in diverse cellular functions. The ability… Expand
Highly Cited
2002
Highly Cited
2002
Human p63RhoGEF, a novel RhoA-specific guanine nucleotide exchange factor, is localized in cardiac sarcomere.
The Rho small GTPases are crucial proteins involved in regulation of signal transduction cascades from extracellular stimuli to… Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE