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ARHGEF11 gene

Known as: KIAA0380, PDZ-RHOGEF, Rho guanine nucleotide exchange factor 11 
 
National Institutes of Health

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Related topics

1 relation
ARHGEF9 gene

Papers overview

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Highly Cited
2012
Highly Cited
2012
Contribution of Common Genetic Variation to the Risk of Type 2 Diabetes in the Mexican Mestizo Population
Several studies have identified nearly 40 different type 2 diabetes susceptibility loci, mainly in European populations, but few… Expand
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2012
2012
Rho GTP exchange factor ARHGEF11 regulates the integrity of epithelial junctions by connecting ZO-1 and RhoA-myosin II signaling.
The organization of the apical junctional complex and its association with the cytoskeleton is essential for the function of… Expand
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2007
2007
PDZRhoGEF and myosin II localize RhoA activity to the back of polarizing neutrophil-like cells
Chemoattractants such as formyl-Met-Leu-Phe (fMLP) induce neutrophils to polarize by triggering divergent pathways that promote… Expand
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2007
2007
Evidence that Rho guanine nucleotide exchange factor 11 (ARHGEF11) on 1q21 is a type 2 diabetes susceptibility gene in the Old Order Amish.
Rho guanine nucleotide exchange factor 11 (ARHGEF11), located on chromosome 1q21, is involved in G protein signaling and is a… Expand
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2007
2007
New functions for a vertebrate Rho guanine nucleotide exchange factor in ciliated epithelia.
Human ARHGEF11, a PDZ-domain-containing Rho guanine nucleotide exchange factor (RhoGEF), has been studied primarily in tissue… Expand
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Highly Cited
2002
Highly Cited
2002
Interaction of plexin-B1 with PDZ domain-containing Rho guanine nucleotide exchange factors.
The Rho family GTPase has been implicated in plexin-B1, a receptor for Semaphorin 4D (Sema4D), mediating signal transduction. Rho… Expand
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2002
2002
Mechanisms for reversible regulation between G13 and Rho exchange factors.
The heterotrimeric G proteins, G(12) and G(13), mediate signaling between G protein-coupled receptors and the monomeric GTPase… Expand
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Highly Cited
2001
Highly Cited
2001
Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins
Glutamate is the main excitatory neurotransmitter in the mammalian central nervous system and is removed from the synaptic cleft… Expand
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2000
2000
Functions of a rho-specific guanine nucleotide exchange factor in neurite retraction. Possible role of a proline-rich motif of KIAA0380 in localization.
The Rho/Rho kinase signaling pathway plays an essential role in neurite retraction and cell rounding in response to G(12/13… Expand
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1999
1999
Rho-specific binding and guanine nucleotide exchange catalysis by KIAA0380, a dbl family member.
Several guanine nucleotide exchange factors (GEFs) for Rho-GTPases have been identified, all of them containing a Dbl homology… Expand
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