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APOBEC3G protein, human

Known as: APOBEC3G, human, CEM-15, CEM15 protein, human 
DNA dC->dU-editing enzyme APOBEC-3G protein (384 aa, ~46 kDa) is encoded by the human APOBEC3G gene. This protein is a member of the cytidine… 
National Institutes of Health

Related topics

Related topics

10 relations
APOBEC DeaminasesAPOBEC3G geneAntiviral ResponseCytidine Deaminase

Broader (1)

APOBEC-3G Deaminase

Narrower (1)

deoxycytidine deaminase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Combinatorial bio-conjugation of gemcitabine and curcumin enables dual drug delivery with synergistic anticancer efficacy and reduced toxicity
The present study seeks to exploit a novel bio-conjugation strategy for improving the biopharmaceutical properties of gemcitabine… 
2006
2006
The radiosensitising effect of difluorodeoxyuridine, a metabolite of gemcitabine, in vitro
Purpose: Gemcitabine is an active antitumour agent with radiosensitising properties. Gemcitabine is rapidly metabolised… 
Highly Cited
2004
Highly Cited
2004
APOBEC3G Targets Specific Virus Species
ABSTRACT Human APOBEC3G (huAPOBEC3G), also known as CEM15, is a broad antiretroviral host factor that deaminates dC to dU in the… 
2004
2004
Intravesical administration of gemcitabine in superficial bladder cancer: a phase I study with pharmacodynamic evaluation
To determine, in a phase I trial, the local and systemic toxicity and pharmacodynamics of intravesical gemcitabine in patients… 
1998
1998
Oral cytarabine ocfosfate in acute myeloid leukemia and non-Hodgkin’s lymphoma – phase I/II studies and pharmacokinetics
Cytosine arabinoside (AraC) is rapidly inactivated via systemic deamination with half-lives ranging from 1 h (i.v.) to 4 h (s.c… 
1991
1991
Synthesis and anticancer and antiviral activities of various 2'- and 3'-methylidene-substituted nucleoside analogues and crystal structure of 2'-deoxy-2'-methylidenecytidine hydrochloride.
Various 2'- and 3'-methylidene-substituted nucleoside analogues have been synthesized and evaluated as potential anticancer and… 
1989
1989
Modulation of deoxynucleotide metabolism by the deoxycytidylate deaminase inhibitor 3,4,5,6-tetrahydrodeoxyuridine.
1987
1987
Tumor-selective metabolism of 5-fluoro-2'-deoxycytidine coadministered with tetrahydrouridine compared to 5-fluorouracil in mice bearing Lewis lung carcinoma.
The metabolic products formed and incorporated into the nucleic acids (RNA and DNA) of mice bearing Lewis lung carcinoma (LLC… 
Highly Cited
1982
Highly Cited
1982
Activities of various enzymes of pyrimidine nucleotide and DNA syntheses in normal and neoplastic human tissues.
The activities of the key enzymes of pyrimidine nucleotide and DNA syntheses in 43 human tumors and 28 normal human tissues were… 
1975
1975
A human-mouse somatic hybrid line selected for human deoxycytidine deaminase
A new selective medium has been developed for cells containing the enzyme deoxycytidine deaminase. This medium contains… 
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