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APOBEC Deaminases

Known as: AID-APOBEC Deaminases, APOBEC Protein, APOBEC Family 
A family of conserved cytidine deaminases that catalyze the DEAMINATION of CYTIDINE to URIDINE. They are characterized by N and C-terminal zinc… 
National Institutes of Health

Related topics

Related topics

12 relations
APOBEC3A protein, humanAPOBEC3B protein, humanAPOBEC3F protein, humanAPOBEC3G protein, human

Papers overview

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2019
2019
CRISPR Base Editing in Induced Pluripotent Stem Cells.
Induced pluripotent stem cells (iPSCs) have demonstrated tremendous potential in numerous disease modeling and regenerative… 
2018
2018
Absence of A3Z3-Related Hypermutations in the env and vif Proviral Genes in FIV Naturally Infected Cats
Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3; A3) proteins comprise an important family of… 
2017
2017
Mechanisms for targeted, purposeful mutation revealed in an APOBEC–DNA complex
Targeted deamination of cytosine bases in DNA by AID/APOBEC-family enzymes is critical for proper immune function, but it also… 
2017
2017
[Cloning, expression and activity identification of human innate immune protein apolipoprotein B mRNA editing enzyme catalytic subunit 3A (APOBEC3A)].
Objective To construct the expression vector of apolipoprotein B mRNA editing enzyme catalytic subunit 3A (APOBEC3A), express… 
2015
2015
APOBEC3H polymorphisms and susceptibility to HIV-1 infection in an Indian population
Human APOBEC3H (A3H) is a member of APOBEC cytidine deaminase family intensively constraining the HIV-1 replication. A3H is known… 
2015
2015
Rebellious enzymes : mutation showers in cancer induced by APOBEC ‘ kataegisters ’ In 2012 , cancer genomics
  • 2015
  • Corpus ID: 9401496
In 2012, cancer genomics saw the addition of a new phrase to its lexicon: kataegis, Greek for thunderstorm and an apt description… 
2014
2014
Mutational signatures in Helicobacter pylori-induced gastric cancer: lessons from new sequencing technologies.
n recent years, tremendous advances in DNA Isequencing technologies have enabled an unprecedented new ability to systematically… 
2014
2014
Funktionsanalyse von Derivaten des HIV-Antagonisten RN18, sowie potentieller weiterer Vif/Apobec-Hemmstoffe mittels eines Zell-basierten Fluoreszenz Screeningverfahrens
Die Moglichkeit, durch Beeinflussung der Interaktion der Gegenspieler Apobec3G und Vif, ein neuartiges Medikament gegen HIV zu… 
2012
2012
Methyl-and Normal-Cytosine Deamination by the Foreign DNA Restriction Enzyme APOBEC 3 A
Multiple studies have indicated that the TET oxidases and, more controversially, the AID/APOBEC deaminases have the capacity to… 
2010
2010
Modeling the intracellular dynamics for Vif-APO mediated HIV-1 virus infection
The viral infectivity factor (Vif) was found to be essential for controlling HIV-1 virus infectivity. It targets cellular… 
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