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APOBEC-3G Deaminase

Known as: APOBEC-Related Protein, APOBEC 3G dC dU Editing Enzyme, APOBEC-3G Protein 
An APOBEC deaminase that functions as an inhibitor of RETROVIRIDAE replication and inhibits the mobility of RETROTRANSPOSONS via deaminase-dependent… 
National Institutes of Health

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APOBEC3G protein, humanAPOBEC3G protein, mouse
In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects

Papers overview

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2014
2014
FHIT loss-induced DNA damage creates optimal APOBEC substrates: Insights into APOBEC-mediated mutagenesis
APOBEC cytidine deaminase activity is a major source of hypermutation in cancer. But previous studies have shown that the TC… 
2013
2013
Dispersed and Conserved Hydrophobic Residues of HIV-1 Vif Are Essential for CBFβ Recruitment and A3G Suppression
ABSTRACT CBFβ was recently found to be a key regulator of the ability of human immunodeficiency virus type 1 (HIV-1) Vif to… 
2010
2010
Polyubiquitination of APOBEC3G Is Essential for Its Degradation by HIV-1 Vif
ABSTRACT Proteasomal degradation of APOBEC3G is a critical step for human immunodeficiency virus type 1 (HIV-1) replication… 
2009
2009
Ethnic differences of two non-synonymous single nucleotide polymorphisms in CDA gene.
Cytidine deaminase, encoded by the CDA gene, catalyzes anti-cancer drugs gemcitabine and ara-C into their respective inactive… 
Highly Cited
2007
Highly Cited
2007
Biochemical Differentiation of APOBEC3F and APOBEC3G Proteins Associated with HIV-1 Life Cycle*
APOBEC3G and APOBEC3F are cytidine deaminase with duplicative cytidine deaminase motifs that restrict HIV-1 replication by… 
2005
2005
Deoxyuridine Is Generated Preferentially in the Nontranscribed Strand of DNA from Cells Expressing Activation-Induced Cytidine Deaminase
Activation-induced cytidine deaminase (AID) is required for somatic hypermutation and class switch recombination of Ig genes in B… 
2004
2004
Structural, kinetic, and mutational studies of the zinc ion environment in tetrameric cytidine deaminase.
The zinc-containing cytidine deaminase (CDA, EC 3.5.4.5) is a pyrimidine salvage enzyme catalyzing the hydrolytic deamination of… 
1984
1984
Use of 5-fluorodeoxycytidine and tetrahydrouridine to exploit high levels of deoxycytidylate deaminase in tumors to achieve DNA- and target-directed therapies.
In view of the 20- to 80-fold elevation of deoxycytidine-5'-phosphate (dCMP) deaminase in many human malignant tumors, we have… 
1982
1982
Activity of serum cytidine deaminase during pregnancy
Summary. A simple and reliable method for the estimation of cytidine deaminase (cytidine aminohydrolase; EC 3.5.4.5) activity in… 
1961
1961
Deoxycytidylate deaminase levels in regenerating rat liver.
Deoxycytidylate deaminase activity and net synthesis of deoxyribonucleic acid (DNA) in vivo were found to increase at… 
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