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APLP1 gene

Known as: AMYLOID BETA A4 PRECURSOR-LIKE PROTEIN 1, AMYLOID PRECURSOR-LIKE PROTEIN 1, amyloid beta precursor like protein 1 
This gene plays a role in synaptic signaling.
National Institutes of Health

Related topics

Related topics

4 relations
APLP1 protein, humanG Protein-Coupled Receptor SignalingSignal Transductionnervous system development

Papers overview

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2012
2012
Deletion of the amyloid precursor-like protein 2 (APLP2) does not affect hippocampal neuron morphology or function
2008
2008
Amyloid Precursor-Like Protein 2 Increases the Endocytosis, Instability, and Turnover of the H2-Kd MHC Class I Molecule1
The defense against the invasion of viruses and tumors relies on the presentation of viral and tumor-derived peptides to CTL by… 
2004
2004
Three-dimensional structure of an independently folded extracellular domain of human amyloid-beta precursor protein.
Cleavage of amyloid-beta precursor protein (APP) by site-specific proteases generates amyloid-beta peptides (Abetas), which are… 
2003
2003
Diverse fibrillar peptides directly bind the Alzheimer’s amyloid precursor protein and amyloid precursor-like protein 2 resulting in cellular accumulation
2003
2003
Accumulation of the amyloid precursor-like protein APLP2 and reduction of APLP1 in retinoic acid-differentiated human neuroblastoma cells upon curcumin-induced neurite retraction.
1998
1998
Fine-scale mapping of a novel dementia gene, PLOSL, by linkage disequilibrium.
Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL; MIM 221770) is a rare hereditary cause of… 
Highly Cited
1997
Highly Cited
1997
Human amyloid precursor-like protein 1--cDNA cloning, ectopic expression in COS-7 cells and identification of soluble forms in the cerebrospinal fluid.
Amyloid precursor-like protein 1 (APLP1) represents an integral membrane type 1 protein of unknown function which was originally… 
1995
1995
Metabolism of the Amyloid Precursor-like Protein 2 in MDCK Cells.
Deposition of β-amyloid peptide in senile plaques is a principal neuropathological hallmark of Alzheimer's disease. β-Amyloid… 
1994
1994
APP gene family: unique age-associated changes in splicing of Alzheimer's βA4-amyloid protein precursor
The betaA4-amyloid protein precursor (APP) is a transmembrane glycoprotein that is the source of the characteristic betaA4… 
Review
1994
Review
1994
Identification and regulation of the high affinity binding site of the Alzheimer's disease amyloid protein precursor (APP) to glycosaminoglycans.
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