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APLP1 gene

Known as: AMYLOID BETA A4 PRECURSOR-LIKE PROTEIN 1, AMYLOID PRECURSOR-LIKE PROTEIN 1, amyloid beta precursor like protein 1 
This gene plays a role in synaptic signaling.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Despite intense research efforts, the physiological function and molecular environment of the amyloid precursor protein has… Expand
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Highly Cited
2007
Highly Cited
2007
Physiological processing of the β-amyloid precursor protein (APP) generates amyloid β-protein, which can assemble into oligomers… Expand
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Highly Cited
2006
Highly Cited
2006
Alzheimer's disease is characterized by β‐amyloid (Aβ) overproduction and tau hyperphosphorylation. Recent studies have shown… Expand
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Highly Cited
2005
Highly Cited
2005
Alzheimer's disease is cytopathologically characterized by loss of synapses and neurons, neuritic amyloid plaques consisting of… Expand
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Highly Cited
2003
Highly Cited
2003
A common feature of many human neurodegenerative diseases is the accumulation of insoluble ubiquitin-containing protein… Expand
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2003
2003
Alzheimer's disease (AD) is genetically linked to the processing of amyloid β protein precursor (AβPP). Aside from being the… Expand
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Highly Cited
2000
Highly Cited
2000
The amyloid precursor protein (APP) involved in Alzheimer's disease is a member of a larger gene family including amyloid… Expand
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Highly Cited
1998
Highly Cited
1998
We have examined the trafficking and metabolism of the beta-amyloid precursor protein (APP), an APP homolog (APLP1), and TrkB in… Expand
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Highly Cited
1997
Highly Cited
1997
Amyloid precursor protein (APP) is a member of a larger gene family including amyloid precursor-like proteins (APLP), APLP2 and… Expand
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Highly Cited
1992
Highly Cited
1992
We have isolated a cDNA from a mouse brain library that encodes a protein whose predicted amino acid sequence is 42% identical… Expand
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