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During tumor progression, immune system phagocytes continually clear apoptotic cancer cells in a process known as efferocytosis… Expand Clathrin–AP-3 association is dispensable for AP-3 vesicle budding from endosomes, which suggests that AP-3–clathrin interactions… Expand PURPOSE
Many rhodopsin mutations that cause retinitis pigmentosa produce misfolded rhodopsin proteins that are retained within… Expand Advanced age is the main risk factor for most chronic diseases and functional deficits in humans, but the fundamental mechanisms… Expand Protein synthesis inhibitor antibiotics are widely used to produce amnesia, and have been recognized to inhibit general or global… Expand The amyloid precursor protein (APP) plays a central role in Alzheimer disease (AD) pathogenesis because sequential cleavages by… Expand Ricin is a potent ribotoxin considered to be a potentially dangerous bioterrorist agent due to its wide availability and the… Expand BACKGROUND
We present a new mouse model for the study of peritoneal adhesions using macrophage Fas-induced apoptosis (Mafia… Expand The activation of an inducible caspase (iCaspase-9) mediates apoptosis of neovascular endothelial cells, and overcomes the… Expand To investigate the function of dimerization of the TRH receptor, a controlled dimerization system was developed. A variant FK506… Expand