AMD3465
National Institutes of Health
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CXCR4 is a chemokine receptor overexpressed in numerous cancer types that plays a key role in invasion and metastases. For this…
Although there have been many new developments in the treatment of leukaemia with the use of new anti-leukaemic agents and stem…
Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL
Stromal-derived factor-1 α (SDF-1α, also termed CXCL12…
Abstract 1826 Poster Board I-852 Patients with multiple myeloma (MM) typically present with the disease spread diffusely…
The importance of inflammation in the initiation and development of atherosclerosis has been extensively studied over the last…
Chronic myeloid leukemia (CML) is driven by constitutively activated Bcr-Abl tyrosine kinase, which causes the defective adhesion…
The chemokine receptor CXCR4 is critically involved in the migration of hematopoietic cells towards the stromal derived factor…
Considerable advances have been made in the last years in the design of derivatives acting as inhibitors of HIV entry and fusion…