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AMD 6221

Known as: (Ru(H(3)DTPA)(Cl)), AMD-6221, AMD6221 
National Institutes of Health

Related topics

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3 relations

Broader (2)

Organometallic CompoundsPentetic Acid
analogs & derivatives

Papers overview

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2011
2011
Antitumor Actions of Ruthenium(III)-Based Nitric Oxide Scavengers and Nitric Oxide Synthase Inhibitors
The role of endogenous nitric oxide (NO) in the growth and vascularization of a rat carcinosarcoma (P22) has been investigated… 
2005
2005
The ruthenium-based nitric oxide scavenger, AMD6221, augments cardiovascular responsiveness to noradrenaline in rats with streptozotocin-induced diabetes.
Highly Cited
2003
Highly Cited
2003
Ruthenium(III) polyaminocarboxylate complexes: efficient and effective nitric oxide scavengers.
The preparation of two Ru(III) polyaminocarboxylate complexes, AMD6245 and AMD6221, and their nitrosyl analogues, AMD6204… 
2003
2003
Increased matrix metalloproteinase activity after canine cardiopulmonary bypass is suppressed by a nitric oxide scavenger.
OBJECTIVES We tested whether nitric oxide scavenging with a ruthenium-based compound (AMD6221) would improve hemodynamics and… 
2002
2002
Mechanistic studies on AMD6221: a ruthenium-based nitric oxide scavenger.
Nitric oxide is a mediator of many disease states. Previous studies have demonstrated that ruthenium(III) polyaminocarboxylates… 
2002
2002
A Ruthenium (III) Polyaminocarboxylate Complex, A Novel Nitric Oxide Scavenger, Enhances Graft Survival and Decreases Nitrosylated Heme Protein in Models of Acute and Delayed Cardiac Transplant…
Nitric oxide (NO) derived from the up-regulation of inducible NO synthase (iNOS) is believed to play an important role in organ… 
2002
2002
Nitric Oxide Scavenger AMD6221 Suppresses Endotoxin-Induced Uveitis (EIU) in Rabbits
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