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ALCAM gene

Known as: Activated Leukocyte Cell Adhesion Molecule Gene, MEMD, ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE 
This gene plays a role in cellular adhesion events involving immune cells, such as monocytes and leukocytes.
National Institutes of Health

Related topics

Related topics

7 relations
ALCAM protein, humanActivated-Leukocyte Cell Adhesion MoleculeCell AdhesionCell-Cell Adhesion Process

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ALCAM wt Allele

Papers overview

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Highly Cited
2013
Highly Cited
2013
Mechanisms of HIV Entry into the CNS: Increased Sensitivity of HIV Infected CD14+CD16+ Monocytes to CCL2 and Key Roles of CCR2, JAM-A, and ALCAM in Diapedesis
As HIV infected individuals live longer, the prevalence of HIV associated neurocognitive disorders is increasing, despite… 
Highly Cited
2007
Highly Cited
2007
Proteomics analysis of Hodgkin lymphoma: identification of new players involved in the cross-talk between HRS cells and infiltrating lymphocytes.
Hodgkin and Reed-Sternberg (HRS) cells in Hodgkin lymphoma (HL) secrete factors that interact with inflammatory background cells… 
Highly Cited
2006
Highly Cited
2006
Quantitative Membrane Proteomics Reveals New Cellular Targets of Viral Immune Modulators
Immunomodulators of pathogens frequently affect multiple cellular targets, thus preventing recognition by different immune cells… 
Highly Cited
2006
Highly Cited
2006
Activated leukocyte cell adhesion molecule is a component of the endothelial junction involved in transendothelial monocyte migration
Highly Cited
2006
Highly Cited
2006
Identification of Clinically Significant Tumor Antigens by Selecting Phage Antibody Library on Tumor Cells in Situ Using Laser Capture Microdissection*S
Much work has been done to develop tumor-targeting antibodies by selecting a phage antibody library on cancer cell lines. However… 
Highly Cited
2004
Highly Cited
2004
The RacGEF Tiam1 inhibits migration and invasion of metastatic melanoma via a novel adhesive mechanism
Rho-like GTPases such as RhoA, Rac1 and Cdc42 are key regulators of actin-dependent cell functions including cell morphology… 
Highly Cited
2001
Highly Cited
2001
ALCAM (CD166): its role in hematopoietic and endothelial development.
A critical role for the endothelium of yolk sac and dorsal aorta has been shown in embryonic hematopoiesis. A stromal cell line… 
Highly Cited
2000
Highly Cited
2000
Coordinate recruitment of E-cadherin and ALCAM to cell-cell contacts by alpha-catenin.
Here we report on the role of alpha-catenin in the cellular localization of activated leukocyte cell adhesion molecule, ALCAM… 
Highly Cited
2000
Highly Cited
2000
Molecular analysis of the hematopoiesis supporting osteoblastic cell line U2-OS.
Highly Cited
1999
Highly Cited
1999
HCA, an immunoglobulin-like adhesion molecule present on the earliest human hematopoietic precursor cells, is also expressed by stromal cells in blood-forming tissues.
We have previously shown that the HCA/ALCAM (CD166) glycoprotein, a member of the immunoglobulin family that mediates both… 
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