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AL 1576

Known as: ALO1576, AL1576, Alcon 1576 
National Institutes of Health

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Papers overview

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2012
2012
Novel Diabetic Mouse Models as Tools for Investigating Diabetic Retinopathy
Objective Mouse models possessing green fluorescent protein (GFP) and/or human aldose reductase (hAR) in vascular tissues have… 
2000
2000
Isolation of a non-covalent aldose reductase-nucleotide-inhibitor complex.
2000
2000
Effects of aldose reductase inhibitors on antioxidant defense in rat and rabbit liver.
Aldose reductase has been implicated in the etiology of diabetic complications, atherosclerosis, and ischemia-reperfusion injury… 
1998
1998
Diabetic-like corneal sensitivity loss in galactose-fed rats ameliorated with aldose reductase inhibitors.
This study investigated whether diabetic-like corneal sensory deficits occur in the galactose-fed rat model of diabetic ocular… 
1998
1998
Mitochondrial aldehyde reductase: identification and characterization in rat liver and kidney cortex.
1990
1990
Chromatographic separation of activated and unactivated forms of aldose reductase.
Highly Cited
1989
Highly Cited
1989
Kinetic and structural effects of activation of bovine kidney aldose reductase.
Aldose reductase, purified to homogeneity from bovine kidney, is converted in a temperature-dependent process from a low-Km/low… 
1989
1989
DNA-synthesis regulation and correlation with inositol trisphosphate levels in cultured bovine retinal capillary pericytes.
1989
1989
Attenuation of phosphoinositidase activity and phosphatidylinositol bisphosphate level of bovine retinal capillary pericytes in high glucose.
1985
1985
Comparison of aldose reductase inhibitors by determination of IC50 with bovine and rat lens extracts.
The inhibition constants of several aldose reductase inhibitors were determined using water-soluble extracts of bovine and rat… 
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