AKT1S1 gene

Known as: PROLINE-RICH AKT SUBSTRATE, 40-KD, AKT1S1, Lobe 
This gene plays a role in the regulation of mTOR signaling.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Reducing the mammalian target of rapamycin (mTOR) activity increases lifespan and health span in a variety of organisms… (More)
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2010
2010
The mTORC1 protein kinase complex consists of mTOR, raptor, mLST8/GbetaL and PRAS40. Previously, we reported that mTOR plays an… (More)
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Highly Cited
2009
Highly Cited
2009
PIM1 is a serine/threonine kinase that has diverse biological roles in cell survival, proliferation and differentiation. PIM1 has… (More)
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Review
2008
Review
2008
The mammalian target of rapamycin (mTOR) is a protein kinase that regulates protein translation, cell growth, and apoptosis… (More)
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Highly Cited
2007
Highly Cited
2007
The heterotrimeric mTORC1 protein kinase nucleates a signaling network that promotes cell growth in response to insulin and… (More)
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Highly Cited
2007
Highly Cited
2007
Insulin stimulates protein synthesis and cell growth by activation of the protein kinases Akt (also known as protein kinase B… (More)
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Highly Cited
2007
Highly Cited
2007
Signaling through the mammalian target of rapamycin complex 1 (mTORC1) is positively regulated by amino acids and insulin. PRAS40… (More)
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Highly Cited
2007
Highly Cited
2007
The protein kinase mammalian target of rapamycin (mTOR) plays an important role in the coordinate regulation of cellular… (More)
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Highly Cited
2007
Highly Cited
2007
Mammalian target of rapamycin (mTOR) functions in two distinct signaling complexes, mTORC1 and mTORC2. In response to insulin and… (More)
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Highly Cited
2007
Highly Cited
2007
Malignant melanoma is the most invasive and deadly form of skin cancer with no effective therapy to treat advanced disease… (More)
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