Trimedazidine alleviates pulmonary artery banding-induced acute right heart dysfunction and activates PRAS40 in rats

@inproceedings{Cao2017TrimedazidineAP,
  title={Trimedazidine alleviates pulmonary artery banding-induced acute right heart dysfunction and activates PRAS40 in rats},
  author={Yunshan Cao and Jiyang Song and Shutong Shen and Heling Fu and Xiang Li and Ying Xu and Aqian Wang and Xinli Li and Min Zhang},
  booktitle={Oncotarget},
  year={2017}
}
The molecular mechanism underlying acute right heart failure (RHF) is poorly understood. We used pulmonary artery banding (PAB) to induce acute RHF characterized by a rapid rise of right ventricular pressure, and then a decrease in right ventricular pressure along with a decrease in blood pressure right after banding. We found higher brain natriuretic… CONTINUE READING