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AKAP12 gene

Known as: A-kinase anchoring protein 12, Src-Suppressed C Kinase Substrate, GRAVIN 
This gene plays a role in signal transduction and angiogenesis.
National Institutes of Health

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4 relations
AKAP12 protein, humanSignal Transductionprotein protein interaction

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AKAP12 wt Allele

Papers overview

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Review
2012
Review
2012
Negative Regulators of Schwann Cell Differentiation—Novel Targets for Peripheral Nerve Therapies?
As myelinating glial cells of the peripheral nervous system, Schwann cells wrap around axons and thereby provide insulation… 
2009
2009
Tumor necrosis factor‐alpha inhibits Schwann cell proliferation by up‐regulating Src‐suppressed protein kinase C substrate expression
Src‐suppressed protein kinase C substrate (SSeCKS) is a protein kinase C substrate protein, which plays an important role in… 
2007
2007
AKAP12, a gene with tumour suppressor properties, is a target of promoter DNA methylation in childhood myeloid malignancies
A‐kinase anchor protein 12 (AKAP12) is a scaffold protein that participates in mitotic regulation and other signalling processes… 
2003
2003
Differential and Regulated Binding of cAMP-dependent Protein Kinase and Protein Kinase C Isoenzymes to Gravin in Human Model Neurons
The membrane cortex has an important role in generating and maintaining spatially and functionally distinct domains in neurons… 
Review
2002
Review
2002
The role of SSeCKS/gravin/AKAP12 scaffolding proteins in the spaciotemporal control of signaling pathways in oncogenesis and development .
Scaffolding proteins are thought to facilitate the efficiency and specificity of enzyme/substrate reactions by coordinating their… 
2002
2002
Induction of Src-suppressed C Kinase Substrate (SSeCKS) in Vascular Endothelial Cells by Bacterial Lipopolysaccharide
We isolated cDNA of the mouse homologue of the src-suppressed C kinase substrate (SSeCKS) and analyzed the effects of… 
2002
2002
Mitogen-induced, FAK-dependent tyrosine phosphorylation of the SSeCKS scaffolding protein.
The ability of mitogens to rapidly induce tyrosine phosphorylation of cellular proteins has been taken as evidence of… 
2001
2001
Intracellular Distribution of Gravin, a PKA and PKC Binding Protein, in Vascular Endothelial Cells
Gravin, a high-molecular-weight protein expressed widely in tissues and cells, is upregulated in cultured endothelial cells under… 
Highly Cited
1999
Highly Cited
1999
Involvement of the protein kinase C substrate, SSeCKS, in the actin-based stellate morphology of mesangial cells.
Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation and proliferation, yet… 
1997
1997
Cell-cycle regulated expression and serine phosphorylation of the myristylated protein kinase C substrate, SSeCKS: Correlation with culture confluency, cell cycle phase and serum response
We recently identified a novel myristylated protein kinase C (PKC) substrate, named SSeCKS (pronounced essex), whose… 
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