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AKAP12 wt Allele

Known as: A-Kinase Anchoring Protein 12 wt Allele, AKAP250, SSeCKS 
Human AKAP12 wild-type allele is located within 6q24-q25 and is approximately 116 kb in length. This allele, which encodes A-kinase anchor protein 12… 
National Institutes of Health

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Related topics

5 relations
6q24-q25AKAP12 protein, humanSignal Transductionprotein protein interaction

Broader (1)

AKAP12 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
LipoxinA4 attenuates acute pancreatitis‐associated acute lung injury by regulating AQP‐5 and MMP‐9 expression, anti‐apoptosis and PKC/SSeCKS‐mediated F‐actin activation
2011
2011
Role for transcription factor TFII‐I in the suppression of SSeCKS/Gravin/Akap12 transcription by Src
The SSeCKS/Gravin/AKAP12 gene, encoding a kinase scaffolding protein with metastasis‐suppressing activity, is transcriptionally… 
2010
2010
SSeCKS is a Suppressor in Schwann Cell Differentiation and Myelination
Src-suppressed protein kinase C substrate (SSeCKS) plays an important role in the differentiation process. In regeneration of… 
2007
2007
The role of TNF-α and its receptors in the production of Src-suppressed C kinase substrate by rat primary type-2 astrocytes
2007
2007
Src suppressed C kinase substrate regulates the lipopolysaccharide-induced TNF-α biosynthesis in rat astrocytes
The protein kinase C (PKC) is known to be a critical component in the signaling cascades that lead to astrocyte-activation. To… 
2004
2004
The expression of src-suppressed C kinase substrate (SSeCKS) and uptake of exogenous particles in endothelial and reticular cells.
Src-suppressed C kinase substrate (SSeCKS), a potent tumor suppressor, plays a role in membrane-cytoskeletal remodeling to… 
Highly Cited
2002
Highly Cited
2002
Calmodulin and cyclin D anchoring sites on the Src-suppressed C kinase substrate, SSeCKS.
SSeCKS and its human orthologue, Gravin, are large scaffolding proteins that are thought to facilitate mitogenic control by… 
2001
2001
Expression of a down-regulated target, SSeCKS, reverses v-Jun-induced transformation of 10T1/2 murine fibroblasts
Line 10T1/2 mouse fibroblast overexpressing the v-Jun oncoprotein were morphologically altered, grew into multilayered foci in… 
Highly Cited
1999
Highly Cited
1999
Involvement of the protein kinase C substrate, SSeCKS, in the actin-based stellate morphology of mesangial cells.
Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation and proliferation, yet… 
1997
1997
Cell-cycle regulated expression and serine phosphorylation of the myristylated protein kinase C substrate, SSeCKS: Correlation with culture confluency, cell cycle phase and serum response
We recently identified a novel myristylated protein kinase C (PKC) substrate, named SSeCKS (pronounced essex), whose… 
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