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AKAP12 wt Allele

Known as: A-Kinase Anchoring Protein 12 wt Allele, AKAP250, SSeCKS 
Human AKAP12 wild-type allele is located within 6q24-q25 and is approximately 116 kb in length. This allele, which encodes A-kinase anchor protein 12… 
National Institutes of Health

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Related topics

5 relations
6q24-q25AKAP12 protein, humanSignal Transductionprotein protein interaction

Broader (1)

AKAP12 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
SSeCKS/Gravin/AKAP12 Inhibits PKCζ-Mediated Reduction of ERK5 Transactivation to Prevent Endotoxin-Induced Vascular dysfunction
SSeCKS/Gravin/AKAP12 is a protein kinase C (PKC) substrate that inhibits the activity of PKC through binding with it. SSeCKS is… 
2018
2018
LipoxinA4 attenuates acute pancreatitis‐associated acute lung injury by regulating AQP‐5 and MMP‐9 expression, anti‐apoptosis and PKC/SSeCKS‐mediated F‐actin activation
2018
2018
SSeCKS/Akap12 suppresses metastatic melanoma lung colonization by attenuating Src-mediated pre-metastatic niche crosstalk
SSeCKS/Gravin/AKAP12 (SSeCKS) controls metastasis-associated PKC and Src signaling through direct scaffolding activity. SSeCKS is… 
2017
2017
SSeCKS/AKAP12 scaffolding functions suppress B16F10-induced peritoneal metastasis by attenuating CXCL9/10 secretion by resident fibroblasts
SSeCKS/Gravin/AKAP12 (SSeCKS) is a kinase scaffolding protein known to suppress metastasis by attenuating tumor-intrinsic PKC… 
2011
2011
The Relationship Between Src-Suppressed C Kinase Substrate and β-1,4 Galactosyltransferase-I in the Process of Lipopolysaccharide-Induced TNF-α Secretion in Rat Primary Astrocytes
Src-suppressed C kinase substrate (SSeCKS), a protein kinase C substrate, is a major lipopolysaccharide (LPS) response protein… 
2007
2007
Src suppressed C kinase substrate regulates the lipopolysaccharide-induced TNF-α biosynthesis in rat astrocytes
The protein kinase C (PKC) is known to be a critical component in the signaling cascades that lead to astrocyte-activation. To… 
2007
2007
Lipopolysaccharide induces expression of SSeCKS in rat lung microvascular endothelial cell
Src-suppressed C kinase substrate (SSeCKS) plays a role in membrane-cytoskeletal remodeling to regulate mitogenesis, cell… 
2004
2004
The expression of src-suppressed C kinase substrate (SSeCKS) and uptake of exogenous particles in endothelial and reticular cells.
Src-suppressed C kinase substrate (SSeCKS), a potent tumor suppressor, plays a role in membrane-cytoskeletal remodeling to… 
Highly Cited
1999
Highly Cited
1999
Involvement of the protein kinase C substrate, SSeCKS, in the actin-based stellate morphology of mesangial cells.
Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation and proliferation, yet… 
1997
1997
Cell-cycle regulated expression and serine phosphorylation of the myristylated protein kinase C substrate, SSeCKS: Correlation with culture confluency, cell cycle phase and serum response
We recently identified a novel myristylated protein kinase C (PKC) substrate, named SSeCKS (pronounced essex), whose… 
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