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AKAP12 wt Allele

Known as: A-Kinase Anchoring Protein 12 wt Allele, AKAP250, SSeCKS 
Human AKAP12 wild-type allele is located within 6q24-q25 and is approximately 116 kb in length. This allele, which encodes A-kinase anchor protein 12… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
SSeCKS/Gravin/AKAP12 (“SSeCKS”) encodes a cytoskeletal protein that regulates G1 → S progression by scaffolding cyclins, protein… Expand
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Highly Cited
2006
Highly Cited
2006
SSeCKS, a Src-suppressed protein kinase C substrate with metastasis suppressor activity, is the rodent orthologue of human gravin… Expand
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Highly Cited
2004
Highly Cited
2004
SSeCKS is a major protein kinase C substrate which has tumour suppressor activity in models of src- and ras-induced oncogenic… Expand
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Highly Cited
2003
Highly Cited
2003
The blood-brain barrier (BBB) is essential for maintaining brain homeostasis and low permeability. BBB maintenance is important… Expand
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Highly Cited
2002
Highly Cited
2002
  • X. Lin, I. Gelman
  • Biochemical and biophysical research…
  • 2002
  • Corpus ID: 29887921
SSeCKS and its human orthologue, Gravin, are large scaffolding proteins that are thought to facilitate mitogenic control by… Expand
Highly Cited
2001
Highly Cited
2001
The molecular mechanisms leading to prostate cancer remain poorly understood, especially concerning the progression to the… Expand
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Highly Cited
1999
Highly Cited
1999
Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation and proliferation, yet… Expand
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Highly Cited
1998
Highly Cited
1998
Activation of protein kinase C (PKC) in many cell types results in cytoskeletal reorganization associated with cell proliferation… Expand
Highly Cited
1997
Highly Cited
1997
SSeCKS (pronounced essex) encodes a major protein kinase C substrate, the expression of which is down-regulated in src- and ras… Expand
Highly Cited
1996
Highly Cited
1996
We previously identified a novel src- and ras-suppressed gene, 322, encoding a mitogenic regulatory function (Lin, X., Nelson, P… Expand
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