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AIN 457
Known as:
AIN-457
, AIN457
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
secukinumab
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Late Breaking Abstract - The biological pathways underlying response to anti-IL-17A (AIN457; secukinumab) therapy differ across severe asthmatic patients
E. Khokhlovich
,
S. Grant
,
+5 authors
S. Kennedy
2017
Corpus ID: 80478577
Asthma stratification efforts have predominantly focused on subgroups defined by levels of circulating and sputum eosinophils. In…
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2013
2013
SAT0142 Immunogenicity of the Novel Anti-Il-17A Antibody, Secukinumab, with Intravenous and Subcutaneous Dosing Regimens in Healthy Subjects and Patients
U. Klein
,
E. Liang
,
B. Vogel
,
F. Kolbinger
,
G. Bruin
,
P. Lloyd
2013
Corpus ID: 71497452
Background Monoclonal antibodies (mAbs) comprise a large and important class of therapeutic biologicals with the potential for…
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Review
2010
Review
2010
IL-17A in Autoimmune Inflammation of the Central Nervous System: A Promising Therapeutic Target in Multiple Sclerosis?~!2009-09-21~!2009-10-28~!2010-07-14~!
B. Ciric
2010
Corpus ID: 14943300
Discovery of the IL-23/Th17 axis brought to an end the era of the Th1/Th2 paradigm and radically advanced our understanding of…
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2010
2010
Trial watch: Targeting IL-17A shows broad promise in autoimmune diseases
V. Kuchroo
Nature reviews. Drug discovery
2010
Corpus ID: 27948583
monoclonal antibody AIN457, which is being developed by Novartis, has shown promising efficacy for the treatment of psoriasis…
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2010
2010
Therapy: Anti-inflammatory hope for AIN457
Emma Leah
Nature Reviews Rheumatology
2010
Corpus ID: 45608624
2010
2010
The Study of IL-17A Expression as a Biomarker for Patients With Active Noninfectious Uveitis Treated With AIN457
R. Buggage
,
H. Richards
,
M. Valentin
,
I. Koroleva
,
T. Dryja
2010
Corpus ID: 82205553
2010
2010
Human Monoclonal Antibody Targeting IL-17A (AIN457) Down-Regulates MM Cell-Growth and Survival and Inhibits Osteoclast Development In Vitro and In Vivo: A Potential Novel Therapeutic Application In…
R. Prabhala
,
M. Fulciniti
,
+15 authors
N. Munshi
2010
Corpus ID: 208486023
Abstract 456 We have previously demonstrated that IL-17 producing TH17cells, a new subset of T helper cells, are significantly…
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