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AIN 457

Known as: AIN-457, AIN457 
 
National Institutes of Health

Papers overview

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2016
2016
We have previously demonstrated that interleukin-17A (IL-17) producing T helper 17 cells are significantly elevated in blood and… Expand
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Review
2016
Review
2016
Secukinumab (also known as AIN-457) is a human monoclonal antibody targeting IL-17A, which has been recently FDA-approved for the… Expand
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2014
2014
The family of interleukin 17 receptors (IL17Rs), subtypes IL17RA-IL17RE, is targeted by the group of pro-inflammatory IL17… Expand
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2014
2014
Anti-cytokine autoantibodies have been widely reported to be present in human plasma, both in healthy subjects and in patients… Expand
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2013
2013
Background Monoclonal antibodies (mAbs) comprise a large and important class of therapeutic biologicals with the potential for… Expand
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2013
2013
To the Editor: Within the lung the T-helper cell interleukin (IL)-17 (also referred to as IL-17A) is recognised as one of the… Expand
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Highly Cited
2010
Highly Cited
2010
Interleukin-17A (IL-17A) is elaborated by the T helper 17 (T(H)17) subset of T(H) cells and exhibits potent proinflammatory… Expand
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2010
2010
  • Emma J. Leah
  • Nature Reviews Rheumatology
  • 2010
  • Corpus ID: 45608624
 
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2010
2010
  • Vijay Kuchroo
  • Nature Reviews Drug Discovery
  • 2010
  • Corpus ID: 27948583
monoclonal antibody AIN457, which is being developed by Novartis, has shown promising efficacy for the treatment of psoriasis… Expand
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