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secukinumab

 
National Institutes of Health

Papers overview

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Review
2019
Review
2019
OBJECTIVE To update evidence-based recommendations for the treatment of patients with ankylosing spondylitis (AS) and… Expand
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Highly Cited
2015
Highly Cited
2015
BACKGROUND Secukinumab is an anti-interleukin-17A monoclonal antibody that has been shown to control the symptoms of ankylosing… Expand
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Highly Cited
2015
Highly Cited
2015
BACKGROUND In a phase 2 study, the inhibition of the interleukin-17A receptor improved signs and symptoms of psoriatic arthritis… Expand
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Highly Cited
2015
Highly Cited
2015
BACKGROUND Interleukin 17A is a proinflammatory cytokine that is implicated in the pathogenesis of psoriatic arthritis. We… Expand
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Highly Cited
2015
Highly Cited
2015
BACKGROUND Secukinumab, a fully human anti-interleukin-17A monoclonal antibody, has shown superior efficacy to etanercept with… Expand
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Highly Cited
2014
Highly Cited
2014
BACKGROUND Interleukin-17A is considered to be central to the pathogenesis of psoriasis. We evaluated secukinumab, a fully human… Expand
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Highly Cited
2013
Highly Cited
2013
BACKGROUND Ankylosing spondylitis is a chronic immune-mediated inflammatory disease characterised by spinal inflammation… Expand
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Highly Cited
2013
Highly Cited
2013
BACKGROUND Conventional systemic therapies for plaque psoriasis have not fully met the needs of patients, and although current… Expand
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Review
2013
Review
2013
Genetic studies and correlative expression data in diseased tissues have pointed to the role of interleukin (IL)-17 and Th17… Expand
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Highly Cited
2012
Highly Cited
2012
Objective The authors tested whether the anti-interleukin (IL)-17A monoclonal antibody secukinumab was safe and effective for the… Expand
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