AIFM1 gene

Known as: APOPTOSIS-INDUCING FACTOR, PDCD8, CMTX4 
 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Dimethyl sulfoxide (DMSO) is an important aprotic solvent that can solubilize a wide variety of otherwise poorly soluble polar… (More)
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Highly Cited
2007
Highly Cited
2007
Nine-day-old harlequin (Hq) mice carrying the hypomorphic apoptosis-inducing factor (AIF)Hq mutation expressed 60% less AIF, 18… (More)
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Highly Cited
2006
Highly Cited
2006
Cell survival after genotoxic stress is determined by a counterbalance of pro- and anti-death factors. Sirtuins (SIRTs) are… (More)
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Highly Cited
2006
Highly Cited
2006
The tumor suppressor p53 plays a pivotal role in suppressing tumorigenesis by inducing genomic stability, cell cycle arrest or… (More)
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Highly Cited
2005
Highly Cited
2005
Mitochondria release proteins that propagate both caspase-dependent and caspase-independent cell death pathways. AIF (apoptosis… (More)
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Highly Cited
2003
Highly Cited
2003
Poly(ADP-ribosylation), primarily via poly(ADP-ribose) polymerase-1 (PARP-1), is a pluripotent cellular process important for… (More)
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Highly Cited
2003
Highly Cited
2003
Heat shock protein 70 (HSP70) can inhibit apoptosis by neutralizing and interacting with apoptosis-inducing factor (AIF), a… (More)
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Highly Cited
2001
Highly Cited
2001
Heat-shock protein 70 (Hsp70) has been reported to block apoptosis by binding apoptosis protease activating factor-1 (Apaf-1… (More)
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Highly Cited
2001
Highly Cited
2001
Programmed cell death is a fundamental requirement for embryogenesis, organ metamorphosis and tissue homeostasis. In mammals… (More)
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Highly Cited
1999
Highly Cited
1999
Mitochondria play a key part in the regulation of apoptosis (cell death). Their intermembrane space contains several proteins… (More)
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